academic article

• GPER modulators: Opportunity Nox on the heels of a class Akt..  The Journal of steroid biochemistry and molecular biology.  :-. 2017
• Twenty years of the G protein-coupled estrogen receptor GPER: Historical and personal perspectives..  The Journal of steroid biochemistry and molecular biology.  :-. 2017
• Obligatory role for GPER in cardiovascular aging and disease..  Science signaling.  9:-. 2016
• Towards a transcriptome-based theranostic platform for unfavorable breast cancer phenotypes..  Proceedings of the National Academy of Sciences of the United States of America.  :-. 2016
• GPER mediates the age-dependent upregulation of the myocardial endothelin system..  Life sciences.  :-. 2016
• GPER/GPR30 Knockout Mice: Effects of GPER on Metabolism..  Methods in molecular biology (Clifton, N.J.).  1366:489-502. 2016
• Regulation of N-Formyl Peptide Receptor Signaling and Trafficking by Arrestin-Src Kinase Interaction..  PloS one.  11:-. 2016
• G protein-coupled estrogen receptor inhibits vascular prostanoid production and activity..  The Journal of endocrinology.  :-. 2015
• Prostanoid-mediated contractions of the carotid artery become Nox2-independent with aging..  Age (Dordrecht, Netherlands).  37:-. 2015
• International Union of Basic and Clinical Pharmacology. XCVII. G Protein-Coupled Estrogen Receptor and Its Pharmacologic Modulators..  Pharmacological reviews.  67:505-540. 2015
• What have we learned about GPER function in physiology and disease from knockout mice?.  The Journal of steroid biochemistry and molecular biology.  :-. 2015
• Effects of Atrazine on Estrogen Receptor α- and G Protein-Coupled Receptor 30-Mediated Signaling and Proliferation in Cancer Cells and Cancer-Associated Fibroblasts..  Environmental health perspectives.  :-. 2015
• Estrogen-mediated inactivation of FOXO3a by the G protein-coupled estrogen receptor GPER..  BMC cancer.  15:-. 2015
• Peptidyl arginine deiminase from Porphyromonas gingivalis abolishes anaphylatoxin C5a activity..  The Journal of biological chemistry.  289:32481-32487. 2014
• Activation of GPER-1 estradiol receptor downregulates production of testosterone in isolated rat Leydig cells and adult human testis. 2014
• Endometrial cancer: molecular and cellular basis of tumor development, novel biomarkers and therapeutic agents, and innovative research approaches..  Obstetrics and gynecology international.  2014:-. 2014
• Endothelin-1 but not angiotensin II contributes to functional aging in murine carotid arteries..  Life sciences.  :-. 2014
• Estrogen biology: new insights into GPER function and clinical opportunities..  Molecular and cellular endocrinology.  389:71-83. 2014
• G Protein-coupled Estrogen Receptor Protects from Atherosclerosis..  Scientific reports.  4:-. 2014
• G protein-coupled estrogen receptor (GPER) regulates mammary tumorigenesis and metastasis..  Molecular cancer research : MCR.  :-. 2014
• GPER mediates estrogen-induced signaling and proliferation in human breast epithelial cells and normal and malignant breast..  Hormones & cancer.  5:146-160. 2014
• GPER-targeted, 99mTc-labeled, nonsteroidal ligands demonstrate selective tumor imaging and in vivo estrogen binding..  Molecular cancer research : MCR.  :-. 2014
• Introduction of D-phenylalanine enhanced the receptor binding affinities of gonadotropin-releasing hormone peptides. 2014
• Alike but not the same: anatomic heterogeneity of estrogen receptor-mediated vasodilation..  Journal of cardiovascular pharmacology.  62:22-25. 2013
• Functional heterogeneity of NADPH oxidase-mediated contractions to endothelin with vascular aging..  Life sciences.  :-. 2013
• G protein-coupled estrogen receptor-selective ligands modulate endometrial tumor growth..  Obstetrics and gynecology international.  2013:-. 2013
• GPER deficiency in male mice results in insulin resistance, dyslipidemia, and a proinflammatory state..  Endocrinology.  154:4136-4145. 2013
• Influences of hydrocarbon linkers on the receptor binding affinities of gonadotropin-releasing hormone peptides. 2013
• Regulation of vascular smooth muscle tone by adipose-derived contracting factor. 2013
• The Concise Guide to PHARMACOLOGY 2013/14: overview..  British journal of pharmacology.  170:1449-1458. 2013
• The G protein-coupled estrogen receptor (GPER) agonist G-1 expands the regulatory T-cell population under TH17-polarizing conditions..  Journal of immunotherapy (Hagerstown, Md. : 1997).  36:190-196. 2013
• Deletion of G protein-coupled estrogen receptor increases endothelial vasoconstriction..  Hypertension.  59:507-512. 2012
• G protein-coupled estrogen receptor: A new therapeutic target in stroke and traumatic brain/spinal cord injury?*..  Critical care medicine.  40:3323-3325. 2012
• GPER regulates endothelin-dependent vascular tone and intracellular calcium..  Life sciences.  91:623-627. 2012
• Synthesis and characterization of tricarbonyl-Re/Tc(I) chelate probes targeting the G protein-coupled estrogen receptor GPER/GPR30..  PloS one.  7:-. 2012
• Testosterone and secondary hypertension: new pieces to the puzzle..  Hypertension.  59:1101-1103. 2012
• Activation of G protein-coupled estrogen receptor induces endothelium-independent relaxation of coronary artery smooth muscle..  American journal of physiology. Endocrinology and metabolism.  301:E882-E888. 2011
• Identification of a GPER/GPR30 antagonist with improved estrogen receptor counterselectivity..  The Journal of steroid biochemistry and molecular biology.  127:358-366. 2011
• Induction of interleukin-10 in the T helper type 17 effector population by the G protein coupled estrogen receptor (GPER) agonist G-1..  Immunology.  134:93-106. 2011
• Mechanisms of estradiol-induced insulin secretion by the G protein-coupled estrogen receptor GPR30/GPER in pancreatic beta-cells..  Endocrinology.  152:3030-3039. 2011
• Mesothelin and GPR30 staining among a spectrum of pancreatic epithelial neoplasms..  International journal of surgical pathology.  19:588-596. 2011
• The G-protein-coupled estrogen receptor GPER in health and disease..  Nature reviews. Endocrinology.  7:715-726. 2011
• GPR30 and estrogen receptor expression: new insights into hormone dependence of inflammatory breast cancer..  Breast cancer research and treatment.  123:51-58. 2010
• Highly efficient synthesis and characterization of the GPR30-selective agonist G-1 and related tetrahydroquinoline analogs..  Organic & biomolecular chemistry.  8:2252-2259. 2010
• Influence of charge on cell permeability and tumor imaging of GPR30-targeted 111in-labeled nonsteroidal imaging agents..  ACS chemical biology.  5:681-690. 2010
• The G protein-coupled receptor GPR30 inhibits proliferation of estrogen receptor-positive breast cancer cells..  Cancer research.  70:1184-1194. 2010
• Detection of intracellular granularity induction in prostate cancer cell lines by small molecules using the HyperCyt high-throughput flow cytometry system..  Journal of biomolecular screening.  14:596-609. 2009
• Duplex high-throughput flow cytometry screen identifies two novel formylpeptide receptor family probes..  Cytometry. Part A : the journal of the International Society for Analytical Cytology.  75:253-263. 2009
• Expression of estrogen receptor GPR30 in the rat spinal cord and in autonomic and sensory ganglia..  Journal of neuroscience research.  87:1610-1619. 2009
• GPR30 predicts poor survival for ovarian cancer..  Gynecologic oncology.  114:465-471. 2009
• High-content screening: flow cytometry analysis..  Methods in molecular biology (Clifton, N.J.).  486:151-165. 2009
• In vivo effects of a GPR30 antagonist..  Nature chemical biology.  5:421-427. 2009
• Regulatory role of G protein-coupled estrogen receptor for vascular function and obesity..  Circulation research.  104:288-291. 2009
• A multifunctional androgen receptor screening assay using the high-throughput Hypercyt flow cytometry system..  Cytometry. Part A : the journal of the International Society for Analytical Cytology.  73:390-399. 2008
• Enhancement of somatostatin-receptor-targeted (177)Lu-[DOTA(0)-Tyr(3)]-octreotide therapy by gemcitabine pretreatment-mediated receptor uptake, up-regulation and cell cycle modulation..  Nuclear medicine and biology.  35:673-678. 2008
• Estrogen signaling through the transmembrane G protein-coupled receptor GPR30..  Annual review of physiology.  70:165-190. 2008
• GPR30: a novel therapeutic target in estrogen-related disease..  Trends in pharmacological sciences.  29:116-123. 2008
• Preclinical development of a neutral, estrogen receptor-targeted, tridentate 99mTc(I)-estradiol-pyridin-2-yl hydrazine derivative for imaging of breast and endometrial cancers..  Journal of nuclear medicine : official publication, Society of Nuclear Medicine.  49:978-986. 2008
• The ins and outs of GPR30: a transmembrane estrogen receptor..  The Journal of steroid biochemistry and molecular biology.  109:350-353. 2008
• Activated N-formyl peptide receptor and high-affinity IgE receptor occupy common domains for signaling and internalization..  Molecular biology of the cell.  18:1410-1420. 2007
• Distribution and characterization of estrogen receptor G protein-coupled receptor 30 in the rat central nervous system..  The Journal of endocrinology.  193:311-321. 2007
• G protein-coupled receptor 30 (GPR30) mediates gene expression changes and growth response to 17beta-estradiol and selective GPR30 ligand G-1 in ovarian cancer cells..  Cancer research.  67:1859-1866. 2007
• Rapid-mix flow cytometry measurements of subsecond regulation of G protein-coupled receptor ternary complex dynamics by guanine nucleotides..  Analytical biochemistry.  371:10-20. 2007
• Some mechanistic insights into GPCR activation from detergent-solubilized ternary complexes on beads..  Advances in protein chemistry.  74:95-135. 2007
• Biomolecular screening of formylpeptide receptor ligands with a sensitive, quantitative, high-throughput flow cytometry platform..  Nature protocols.  1:59-66. 2006
• Glutathione-S-transferase-green fluorescent protein fusion protein reveals slow dissociation from high site density beads and measures free GSH..  Cytometry. Part A : the journal of the International Society for Analytical Cytology.  69:326-334. 2006
• Virtual and biomolecular screening converge on a selective agonist for GPR30..  Nature chemical biology.  2:207-212. 2006
• High-throughput screening with HyperCyt flow cytometry to detect small molecule formylpeptide receptor ligands..  Journal of biomolecular screening.  10:374-382. 2005
• Integration of virtual screening with high-throughput flow cytometry to identify novel small molecule formylpeptide receptor antagonists..  Molecular pharmacology.  68:1301-1310. 2005
• Post-high-throughput screening analysis: an empirical compound prioritization scheme..  Journal of biomolecular screening.  10:419-426. 2005
• Conformational regulation of alpha 4 beta 1-integrin affinity by reducing agents. "Inside-out" signaling is independent of and additive to reduction-regulated integrin activation..  The Journal of biological chemistry.  279:32435-32443. 2004
• Flow cytometry for high-throughput, high-content screening..  Current opinion in chemical biology.  8:392-398. 2004
• N-formyl peptide receptors cluster in an active raft-associated state prior to phosphorylation..  The Journal of biological chemistry.  279:45175-45184. 2004
• FRET detection of cellular alpha4-integrin conformational activation..  Biophysical journal.  85:3951-3962. 2003
• Ligand-receptor-G-protein molecular assemblies on beads for mechanistic studies and screening by flow cytometry..  Molecular pharmacology.  64:1227-1238. 2003
• Synthesis and evaluation of novel gonadotropin-releasing hormone receptor-targeting peptides..  Bioconjugate chemistry.  22:1682-1689.
• The G protein-coupled estrogen receptor GPER/GPR30 as a regulator of cardiovascular function.