selected publications
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academic article
- Trigeminal neuropathic pain is alleviated by inhibition of Cav3.3 T-type calcium channels in mice.. Channels (Austin, Tex.). 15:31-37. 2021
- Effect of acetyl-L-carnitine on hypersensitivity in acute recurrent caerulein-induced pancreatitis and microglial activation along the brain's pain circuitry.. World journal of gastroenterology. 27:794-814. 2021
- Manganese-enhanced MRI reveals changes within brain anxiety and aversion circuitry in rats with chronic neuropathic pain- and anxiety-like behaviors.. NeuroImage. 223:-. 2020
- The Therapeutic Effectiveness of Full Spectrum Hemp Oil Using a Chronic Neuropathic Pain Model.. Life (Basel, Switzerland). 10:-. 2020
- Minimally Invasive Oral Surgery Induction of the FRICT-ION Chronic Neuropathic Pain Model.. Bio-protocol. 10:-. 2020
- Building and Testing PPARγ Therapeutic ELB00824 with an Improved Therapeutic Window for Neuropathic Pain.. Molecules (Basel, Switzerland). 25:-. 2020
- Tyrosine Kinase Inhibitors Reduce NMDA NR1 Subunit Expression, Nuclear Translocation, and Behavioral Pain Measures in Experimental Arthritis.. Frontiers in physiology. 11:-. 2020
- Sustained relief of trigeminal neuropathic pain by a blood-brain barrier penetrable PPAR gamma agonist.. Molecular pain. 15:-. 2019
- Combination Drug Therapy of Pioglitazone and D-cycloserine Attenuates Chronic Orofacial Neuropathic Pain and Anxiety by Improving Mitochondrial Function Following Trigeminal Nerve Injury.. The Clinical journal of pain. 34:168-177. 2018
- Histone deacetylase inhibitors prevent persistent hypersensitivity in an orofacial neuropathic pain model.. Molecular pain. 14:-. 2018
- Punctate Midline Myelotomy Reduces Pain Responses in a Rat Model of Lumbar Spine Pain: Evidence that the Postsynaptic Dorsal Column Pathway Conveys Pain from the Axial Spine.. Cureus. 10:-. 2018
- Ensuring due process in the IACUC and animal welfare setting: considerations in developing noncompliance policies and procedures for institutional animal care and use committees and institutional officials.. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 31:4216-4225. 2017
- Inflammatory 'double hit' model of temporomandibular joint disorder with elevated CCL2, CXCL9, CXCL10, RANTES and behavioural hypersensitivity in TNFR1/R2-/- mice.. European journal of pain (London, England). 21:1209-1223. 2017
- PPARγ Agonists Attenuate Trigeminal Neuropathic Pain.. The Clinical journal of pain. 33:1071-1080. 2017
- The noradrenergic locus coeruleus as a chronic pain generator.. Journal of neuroscience research. 95:1336-1346. 2017
- Disulfide high mobility group box-1 causes bladder pain through bladder Toll-like receptor 4.. BMC physiology. 17:-. 2017
- A Mouse Model of Chronic Pancreatitis Induced by an Alcohol and High Fat Diet.. The open pain journal. 10:81-89. 2017
- Transdermal cannabidiol reduces inflammation and pain-related behaviours in a rat model of arthritis.. European journal of pain (London, England). 20:936-948. 2016
- GABA-A receptor activity in the noradrenergic locus coeruleus drives trigeminal neuropathic pain in the rat; contribution of NAα1 receptors in the medial prefrontal cortex.. Neuroscience. 334:148-159. 2016
- Efficacy of Herpes Simplex Virus Vector Encoding the Human Preproenkephalin Gene for Treatment of Facial Pain in Mice.. Journal of oral & facial pain and headache. 30:42-50. 2016
- Protease-Activated Receptor 4 Induces Bladder Pain through High Mobility Group Box-1.. PloS one. 11:-. 2016
- Alcohol and high fat induced chronic pancreatitis: TRPV4 antagonist reduces hypersensitivity.. Neuroscience. 311:166-179. 2015
- Dysregulated TNFα promotes cytokine proteome profile increases and bilateral orofacial hypersensitivity.. Neuroscience. 300:493-507. 2015
- Trigeminal Inflammatory Compression (TIC) injury induces chronic facial pain and susceptibility to anxiety-related behaviors.. Neuroscience. 295:126-138. 2015
- Catechol-O-methyltransferase inhibition alters pain and anxiety-related volitional behaviors through activation of β-adrenergic receptors in the rat.. Neuroscience. 290:561-569. 2015
- Macrophage Migration Inhibitory Factor Mediates PAR-Induced Bladder Pain.. PloS one. 10:-. 2015
- Persistent neuropathic pain influences persistence behavior in rats.. Journal of oral & facial pain and headache. 29:183-192. 2015
- Pharmacological attenuation of chronic alcoholic pancreatitis induced hypersensitivity in rats.. World journal of gastroenterology. 21:836-853. 2015
- Cannabinoid receptor 2 agonist attenuates pain related behavior in rats with chronic alcohol/high fat diet induced pancreatitis.. Molecular pain. 10:-. 2014
- A rat knockout model implicates TRPC4 in visceral pain sensation.. Neuroscience. 262:165-175. 2014
- Pine oil effects on chemical and thermal injury in mice and cultured mouse dorsal root ganglion neurons.. Phytotherapy research : PTR. 28:252-260. 2014
- Prolonged high fat/alcohol exposure increases TRPV4 and its functional responses in pancreatic stellate cells.. American journal of physiology. Regulatory, integrative and comparative physiology. 304:R702-R711. 2013
- Excitatory amino acids display compartmental disparity between plasma and synovial fluid in clinical arthropathies.. International journal of clinical and experimental pathology. 6:492-497. 2013
- Orofacial neuropathic pain mouse model induced by Trigeminal Inflammatory Compression (TIC) of the infraorbital nerve.. Molecular brain. 5:-. 2012
- Gene expression profiling and endothelin in acute experimental pancreatitis.. World journal of gastroenterology. 18:4257-4269. 2012
- Trigeminal nerve injury ErbB3/ErbB2 promotes mechanical hypersensitivity.. Anesthesiology. 117:381-388. 2012
- Chronic inflammation and pain in a tumor necrosis factor receptor (TNFR) (p55/p75-/-) dual deficient murine model.. Translational research : the journal of laboratory and clinical medicine. 160:84-94. 2012
- Rat models of pancreatitis pain.. Methods in molecular biology (Clifton, N.J.). 851:223-238. 2012
- Impact of central and peripheral TRPV1 and ROS levels on proinflammatory mediators and nociceptive behavior.. Molecular pain. 6:-. 2010
- A peripheral neuroimmune link: glutamate agonists upregulate NMDA NR1 receptor mRNA and protein, vimentin, TNF-alpha, and RANTES in cultured human synoviocytes.. American journal of physiology. Regulatory, integrative and comparative physiology. 298:R584-R598. 2010
- Tumor necrosis factor-alpha (TNF-alpha) enhances functional thermal and chemical responses of TRP cation channels in human synoviocytes.. Molecular pain. 5:-. 2009
- Central lateral thalamic neurons receive noxious visceral mechanical and chemical input in rats.. Journal of neurophysiology. 102:244-258. 2009
- Reactive oxygen species mediate TNFR1 increase after TRPV1 activation in mouse DRG neurons.. Molecular pain. 5:-. 2009
- Gene therapy for pancreatitis pain.. Gene therapy. 16:483-492. 2009
- fMRI of supraspinal areas after morphine and one week pancreatic inflammation in rats.. NeuroImage. 44:23-34. 2009
- Joint capsule treatment with enkephalin-encoding HSV-1 recombinant vector reduces inflammatory damage and behavioural sequelae in rat CFA monoarthritis.. The European journal of neuroscience. 27:1153-1165. 2008
- Enkephalin-encoding herpes simplex virus-1 decreases inflammation and hotplate sensitivity in a chronic pancreatitis model.. Molecular pain. 4:-. 2008
- Plasticity in intact A delta- and C-fibers contributes to cold hypersensitivity in neuropathic rats.. Neuroscience. 150:182-193. 2007
- Treatment of inflamed pancreas with enkephalin encoding HSV-1 recombinant vector reduces inflammatory damage and behavioral sequelae.. Molecular therapy : the journal of the American Society of Gene Therapy. 15:1812-1819. 2007
- Thermosensitive TRP ion channels mediate cytosolic calcium response in human synoviocytes.. American journal of physiology. Cell physiology. 291:C424-C432. 2006
- Increased release of serotonin in the spinal cord during low, but not high, frequency transcutaneous electric nerve stimulation in rats with joint inflammation.. Archives of physical medicine and rehabilitation. 87:1137-1140. 2006
- Chapter 9 The dorsal horn and hyperalgesia.. Handbook of clinical neurology. 81:103-125. 2006
- Upregulation of the phosphorylated form of CREB in spinothalamic tract cells following spinal cord injury: relation to central neuropathic pain.. Neuroscience letters. 384:139-144. 2005
- Transcriptional profiling of spinal cord injury-induced central neuropathic pain.. Journal of neurochemistry. 95:998-1014. 2005
- Proton-sensing G protein-coupled receptor mobilizes calcium in human synovial cells.. American journal of physiology. Cell physiology. 289:C601-C608. 2005
- Exogenous Bcl-xL fusion protein spares neurons after spinal cord injury.. Journal of neuroscience research. 79:628-637. 2005
- Role of neurogenic inflammation in pancreatitis and pancreatic pain.. Neuro-Signals. 14:158-165. 2005
- Excitatory amino acids, TNF-alpha, and chemokine levels in synovial fluids of patients with active arthropathies.. Clinical and experimental immunology. 137:621-627. 2004
- Intrathecal gabapentin enhances the analgesic effects of subtherapeutic dose morphine in a rat experimental pancreatitis model.. Anesthesiology. 101:759-765. 2004
- NMDA receptors and associated signaling pathways: a role in knee joint blood flow regulation.. European journal of pharmacology. 499:155-161. 2004
- Attenuation of nociception in a model of acute pancreatitis by an NK-1 antagonist.. Pharmacology, biochemistry, and behavior. 77:631-640. 2004
- Restoration of spontaneous exploratory behaviors with an intrathecal NMDA receptor antagonist or a PKC inhibitor in rats with acute pancreatitis.. Pharmacology, biochemistry, and behavior. 77:145-153. 2004
- Comparison of microdialysis and push-pull perfusion for retrieval of serotonin and norepinephrine in the spinal cord dorsal horn.. Journal of neuroscience methods. 126:187-194. 2003
- Mechanical sensation and pain thresholds in patients with chronic arthropathies.. The journal of pain. 4:203-211. 2003
- Intrathecal coadministration of D-APV and morphine is maximally effective in a rat experimental pancreatitis model.. Anesthesiology. 98:734-740. 2003
- Nociception in persistent pancreatitis in rats: effects of morphine and neuropeptide alterations.. Anesthesiology. 98:474-484. 2003
- DNA microarray analysis of the contused spinal cord: effect of NMDA receptor inhibition.. Journal of neuroscience research. 68:406-423. 2002
- Rapid changes in expression of glutamate transporters after spinal cord injury.. Brain research. 927:104-110. 2002
- Group I metabotropic glutamate receptor antagonists block secondary thermal hyperalgesia in rats with knee joint inflammation.. The Journal of pharmacology and experimental therapeutics. 300:149-156. 2002
- Bcl-xL expression after contusion to the rat spinal cord.. Journal of neurotrauma. 18:1267-1278. 2001
- Responses of rat dorsal column neurons to pancreatic nociceptive stimulation.. Neuroreport. 12:2527-2530. 2001
- The role of the dorsal column pathway in visceral nociception.. Current pain and headache reports. 5:20-26. 2001
- Arthritic calcitonin/alpha calcitonin gene-related peptide knockout mice have reduced nociceptive hypersensitivity.. Pain. 89:265-273. 2001
- Do nociceptive signals from the pancreas travel in the dorsal column?. Pain. 89:207-220. 2001
- Effects of baclofen on colon inflammation-induced Fos, CGRP and SP expression in spinal cord and brainstem.. Brain research. 889:118-130. 2001
- Rodent model of chronic central pain after spinal cord contusion injury and effects of gabapentin.. Journal of neurotrauma. 17:1205-1217. 2000
- Amino acid release into the knee joint: key role in nociception and inflammation.. Pain. 86:69-74. 2000
- Punctate midline myelotomy for the relief of visceral cancer pain.. Journal of neurosurgery. 92:125-130. 2000
- Excitatory amino acid profiles of synovial fluid from patients with arthritis.. The Journal of rheumatology. 27:739-745. 2000
- Increased blood pressure in alpha-calcitonin gene-related peptide/calcitonin gene knockout mice.. Hypertension (Dallas, Tex. : 1979). 35:470-475. 2000
- The Role of Type 1 Metabotropic Glutamate Receptors in the Generation of Dorsal Root Reflexes Induced by Acute Arthritis or the Spinal Infusion of 4-Aminopyridine in the Anesthetized Rat.. The journal of pain. 1:151-161. 2000
- Visceral nociception.. Current review of pain. 4:478-487. 2000
- Ascending projections from the area around the spinal cord central canal: A Phaseolus vulgaris leucoagglutinin study in rats.. The Journal of comparative neurology. 415:341-367. 1999
- A visceral pain pathway in the dorsal column of the spinal cord.. Proceedings of the National Academy of Sciences of the United States of America. 96:7675-7679. 1999
- Dorsal column lesion prevents mechanical hyperalgesia and allodynia in osteotomy model.. Pain. 82:73-80. 1999
- Gabapentin attenuates nociceptive behaviors in an acute arthritis model in rats.. The Journal of pharmacology and experimental therapeutics. 290:214-219. 1999
- Reversal of weightlessness-induced musculoskeletal losses with androgens: quantification by MRI.. Journal of applied physiology (Bethesda, Md. : 1985). 86:1841-1846. 1999
- Nicotinic cholinergic receptors: potential targets for inflammatory pain relief.. Pain. 80:291-299. 1999
- Receptor for calcitonin gene-related peptide: localization in the dorsal and ventral spinal cord.. Neuroscience. 92:1389-1397. 1999
- Dihydropyridine receptor isoform expression in adult rat skeletal muscle.. Pflugers Archiv : European journal of physiology. 436:309-314. 1998
- Peripheral morphine administration blocks the development of hyperalgesia and allodynia after bone damage in the rat.. Anesthesiology. 89:190-201. 1998
- S-(+)-3-isobutylgaba and its stereoisomer reduces the amount of inflammation and hyperalgesia in an acute arthritis model in the rat.. The Journal of pharmacology and experimental therapeutics. 285:533-538. 1998
- Changes in nitric oxide synthase isoforms in the spinal cord of rat following induction of chronic arthritis.. Experimental brain research. 118:457-465. 1998
- Dorsal column lesions reverse the reduction of homecage activity in rats with pancreatitis.. Neuroreport. 8:3795-3800. 1997
- Enhanced withdrawal responses to mechanical and thermal stimuli after bone injury.. Pain. 73:325-337. 1997
- Sensitization of postsynaptic dorsal column neuronal responses by colon inflammation.. Neuroreport. 8:3267-3273. 1997
- Nucleus gracilis: an integrator for visceral and somatic information.. Journal of neurophysiology. 78:521-527. 1997
- Differential roles of neurokinin 1 and neurokinin 2 receptors in the development and maintenance of heat hyperalgesia induced by acute inflammation.. British journal of pharmacology. 120:1263-1273. 1997
- Excitatory amino acid receptor involvement in peripheral nociceptive transmission in rats.. European journal of pharmacology. 324:169-177. 1997
- Blockade of joint inflammation and secondary hyperalgesia by L-NAME, a nitric oxide synthase inhibitor.. Neuroreport. 8:895-899. 1997
- Surgical interruption of a midline dorsal column visceral pain pathway. Case report and review of the literature.. Journal of neurosurgery. 86:538-542. 1997
- Neuroanatomy of the pain system and of the pathways that modulate pain.. Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society. 14:2-31. 1997
- Dorsal root reflexes in articular afferents occur bilaterally in a chronic model of arthritis in rats.. Journal of neurophysiology. 76:4190-4193. 1996
- Ultrastructural localization of glutamate receptor subunits (NMDAR1, AMPA GluR1 and GluR2/3) and spinothalamic tract cells.. Neuroreport. 7:2581-2585. 1996
- Is there a pathway in the posterior funiculus that signals visceral pain?. Pain. 67:291-305. 1996
- Pelvic visceral input into the nucleus gracilis is largely mediated by the postsynaptic dorsal column pathway.. Journal of neurophysiology. 76:2675-2690. 1996
- Visceral nociceptive input into the ventral posterolateral nucleus of the thalamus: a new function for the dorsal column pathway.. Journal of neurophysiology. 76:2661-2674. 1996
- Association of spinal lamina I projections with brainstem catecholamine neurons in the monkey.. Experimental brain research. 110:151-162. 1996
- Potentiation of thalamic responses to colorectal distension by visceral inflammation.. Neuroreport. 7:1635-1639. 1996
- An I2 imidazoline ligand, RS 45041, potentiates hyperalgesia in acute arthritis.. Neuroreport. 7:1497-1501. 1996
- Cooperative mechanisms of neurotransmitter action in central nervous sensitization.. Progress in brain research. 110:151-166. 1996
- Fiber types contributing to dorsal root reflexes induced by joint inflammation in cats and monkeys.. Journal of neurophysiology. 74:981-989. 1995
- Dexamethasone and activators of the protein kinase A and C signal transduction pathways regulate neuronal calcitonin gene-related peptide expression and release.. Brain research. 686:77-86. 1995
- NGF-producing transfected 3T3 cells: behavioral and histological assessment of transplants in nigral lesioned rats.. Journal of neuroscience research. 41:367-373. 1995
- Comments on editorials: Berkley, PAIN, 70 (1997) 1-2 and Gybels, PAIN, 70 (1997) 103-107.. Pain. 101-102. 1998