selected publications
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academic article
- Activation of Rho Family GTPases by Small Molecules.. ACS chemical biology. 13:1514-1524. 2018
- High-Throughput Flow Cytometry Identifies Small-Molecule Inhibitors for Drug Repurposing in T-ALL.. SLAS Discovery. 23:732-741. 2018
- A high-throughput phenotypic screen of cytotoxic T lymphocyte lytic granule exocytosis reveals candidate immunosuppressants.. Journal of biomolecular screening. 20:359-371. 2015
- Selective chemical inhibition of agr quorum sensing in Staphylococcus aureus promotes host defense with minimal impact on resistance. 2014
- Identification of Isoxsuprine Hydrochloride as a Neuroprotectant in Ischemic Stroke through Cell-Based High-Throughput Screening. 2014
- Elastomeric negative acoustic contrast particles for affinity capture assays.. Analytical chemistry. 85:2208-2215. 2013
- Fluorescent substrates for flow cytometric evaluation of efflux inhibition in ABCB1, ABCC1, and ABCG2 transporters.. Analytical biochemistry. 437:77-87. 2013
- The University of New Mexico Center for Molecular Discovery.. Combinatorial chemistry & high throughput screening. 17:256-265. 2013
- A Selective ATP-Binding Cassette Subfamily G Member 2 Efflux Inhibitor Revealed via High-Throughput Flow Cytometry.. Journal of biomolecular screening. :-. 2012
- Cluster cytometry for high-capacity bioanalysis.. Cytometry. Part A : the journal of the International Society for Analytical Cytology. 81:419-429. 2012
- Identification of a small molecule yeast TORC1 inhibitor with a multiplex screen based on flow cytometry.. ACS chemical biology. 7:715-722. 2012
- A miniature Couette to generate shear for flow cytometry: studying real-time modulation of intracellular calcium in monocytic cells.. Cytometry. Part A : the journal of the International Society for Analytical Cytology. 79:233-240. 2011
- Drug Repurposing from an Academic Perspective.. Drug discovery today. Therapeutic strategies. 8:61-69. 2011
- Drug Repurposing from an Academic Perspective.. Drug discovery today. Therapeutic strategies. 8:61-69. 2011
- Drug Repurposing from an Academic Perspective.. Drug discovery today. Therapeutic strategies. 8:61-69. 2011
- High-throughput screen for the chemical inhibitors of antiapoptotic bcl-2 family proteins by multiplex flow cytometry.. Assay and drug development technologies. 9:465-474. 2011
- Simultaneous in vitro molecular screening of protein-peptide interactions by flow cytometry, using six Bcl-2 family proteins as examples.. Nature protocols. 6:943-952. 2011
- High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors.. Assay and drug development technologies. 8:37-46. 2010
- Identification of a small GTPase inhibitor using a high-throughput flow cytometry bead-based multiplex assay.. Journal of biomolecular screening. 15:10-20. 2010
- Profiling a Selective Probe for RTG Branch of Yeast TORC1 Signaling Pathway 2010
- Recognition of decay accelerating factor and alpha(v)beta(3) by inactivated hantaviruses: Toward the development of high-throughput screening flow cytometry assays.. Analytical biochemistry. 402:151-160. 2010
- Selective Bcl-2 Inhibitor Probes 2010
- Selective Efflux Inhibition of ATP-binding Cassette Sub-family G Member 2 2010
- Detection of intracellular granularity induction in prostate cancer cell lines by small molecules using the HyperCyt high-throughput flow cytometry system.. Journal of biomolecular screening. 14:596-609. 2009
- Detection of intracellular granularity induction in prostate cancer cell lines by small molecules using the HyperCyt high-throughput flow cytometry system.. Journal of biomolecular screening. 14:596-609. 2009
- Detection of intracellular granularity induction in prostate cancer cell lines by small molecules using the HyperCyt high-throughput flow cytometry system.. Journal of biomolecular screening. 14:596-609. 2009
- A novel fluorescent cross-reactive formylpeptide receptor/formylpeptide receptor-like 1 hexapeptide ligand.. Cytometry. Part A : the journal of the International Society for Analytical Cytology. 75:264-270. 2009
- Detection of intracellular granularity induction in prostate cancer cell lines by small molecules using the HyperCyt high-throughput flow cytometry system.. Journal of biomolecular screening. 14:596-609. 2009
- Discovery of selective probes and antagonists for G-protein-coupled receptors FPR/FPRL1 and GPR30.. Current topics in medicinal chemistry. 9:1227-1236. 2009
- Duplex high-throughput flow cytometry screen identifies two novel formylpeptide receptor family probes.. Cytometry. Part A : the journal of the International Society for Analytical Cytology. 75:253-263. 2009
- High-content screening: flow cytometry analysis.. Methods in molecular biology (Clifton, N.J.). 486:151-165. 2009
- A multifunctional androgen receptor screening assay using the high-throughput Hypercyt flow cytometry system.. Cytometry. Part A : the journal of the International Society for Analytical Cytology. 73:390-399. 2008
- High-throughput screening for daunorubicin-mediated drug resistance identifies mometasone furoate as a novel ABCB1-reversal agent.. Journal of biomolecular screening. 13:185-193. 2008
- High-throughput flow cytometry for drug discovery.. Expert opinion on drug discovery. 2:685-696. 2007
- Steroid-binding G-protein-coupled receptors: new drug discovery targets for old ligands.. Expert opinion on drug discovery. 1:137-150. 2006
- Biomolecular screening of formylpeptide receptor ligands with a sensitive, quantitative, high-throughput flow cytometry platform.. Nature protocols. 1:59-66. 2006
- Heat shock protein 70 and glycoprotein 96 are differentially expressed on the surface of malignant and nonmalignant breast cells.. Cell stress & chaperones. 11:334-342. 2006
- Virtual and biomolecular screening converge on a selective agonist for GPR30.. Nature chemical biology. 2:207-212. 2006
- High-throughput screening with HyperCyt flow cytometry to detect small molecule formylpeptide receptor ligands.. Journal of biomolecular screening. 10:374-382. 2005
- Integration of virtual screening with high-throughput flow cytometry to identify novel small molecule formylpeptide receptor antagonists.. Molecular pharmacology. 68:1301-1310. 2005
- Post-high-throughput screening analysis: an empirical compound prioritization scheme.. Journal of biomolecular screening. 10:419-426. 2005
- Techniques: GPCR assembly, pharmacology and screening by flow cytometry.. Trends in pharmacological sciences. 25:663-669. 2004
- High-throughput microfluidic mixing and multiparametric cell sorting for bioactive compound screening.. Journal of biomolecular screening. 9:103-111. 2004
- An investigation of liquid carryover and sample residual for a high-throughput flow cytometer sample delivery system.. Analytical chemistry. 76:3810-3817. 2004
- Conformational regulation of alpha 4 beta 1-integrin affinity by reducing agents. "Inside-out" signaling is independent of and additive to reduction-regulated integrin activation.. The Journal of biological chemistry. 279:32435-32443. 2004
- Flow cytometry for high-throughput, high-content screening.. Current opinion in chemical biology. 8:392-398. 2004
- Alpha4beta1 integrin affinity changes govern cell adhesion. 2003
- Flow cytometric analysis of ligand-receptor interactions and molecular assemblies.. Annual review of biophysics and biomolecular structure. 31:97-119. 2002
- High throughput flow cytometry.. Cytometry. 44:83-90. 2001
- Expression of P-selectin at low site density promotes selective attachment of eosinophils over neutrophils.. Journal of immunology (Baltimore, Md. : 1950). 165:404-410. 2000
- Plug flow cytometry: An automated coupling device for rapid sequential flow cytometric sample analysis.. Cytometry. 37:156-159. 1999
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article
- Advancing Biological Understanding and Therapeutics Discovery with Small-Molecule Probes.. 1252-1265. 2015
- Flow Cytometry: Impact on Early Drug Discovery.. Journal of biomolecular screening. -. 2015