A crowdsourcing evaluation of the NIH chemical probes. Academic Article uri icon

start page

  • 441

end page

  • 447

abstract

  • Between 2004 and 2008, the US National Institutes of Health Molecular Libraries and Imaging initiative pilot phase funded 10 high-throughput screening centers, resulting in the deposition of 691 assays into PubChem and the nomination of 64 chemical probes. We crowdsourced the Molecular Libraries and Imaging initiative output to 11 experts, who expressed medium or high levels of confidence in 48 of these 64 probes.

date/time value

  • 2009

Digital Object Identifier (DOI)

  • 10.1038/nchembio0709-441

PubMed Identifier

  • 19536101

volume

  • 5

number

  • 7

keywords

  • Databases, Factual
  • Decision Making
  • Drug Discovery
  • Molecular Probe Techniques
  • Molecular Probes
  • National Institutes of Health (U.S.)
  • Small Molecule Libraries
  • United States