has collaborator
- Matlawska-Wasowska, Ksenia Faculty Member
- Ness, Scott Professor, Cancer Genomics
- Contact Info
- (505) 272-4195
- Websites
Kang, Huining
Associate Professor
Positions
- Associate Professor, Department of Internal Medicine
- Affiliation
- Publications
- Research
- Contact
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Affiliation
Publications
selected publications
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academic article
- Epigenetic silencing of SOCS5 potentiates JAK-STAT signaling and progression of T-cell acute lymphoblastic leukemia.. Cancer Sciecne. 110:1931-1946. 2019
- Ovarian Tumor Microenvironment Signaling: Convergence on the Rac1 GTPase.. Cancers. 10:-. 2018
- Dysregulated transcriptional networks in KMT2A- and MLLT10-rearranged T-ALL.. Biomarker research. 6:-. 2018
- MLL rearrangements impact outcome in HOXA-deregulated T-lineage acute lymphoblastic leukemia: A children's oncology group study.. Leukemia. :-. 2016
- Gene Expression Studies on Human Trisomy 21 iPSCs and Neurons: Towards Mechanisms Underlying Down's Syndrome and Early Alzheimer's Disease-Like Pathologies.. Methods in molecular biology (Clifton, N.J.). 1303:247-265. 2016
- Recurrent Fusions in MYB and MYBL1 Define a Common, Transcription Factor-Driven Oncogenic Pathway in Salivary Gland Adenoid Cystic Carcinoma.. Cancer discovery. :-. 2015
- A novel pharmacologic activity of ketorolac for therapeutic benefit in ovarian cancer patients.. Clinical cancer research : an official journal of the American Association for Cancer Research. :-. 2015
- Scoring of MYC protein expression in diffuse large B-cell lymphomas: concordance rate among hematopathologists.. Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc. :-. 2014
- A retrospective study to assess the relative value of peripheral blood, bone marrow aspirate and biopsy morphology, immunohistochemical stains, and flow cytometric analysis in the diagnosis of chronic B cell lymphoproliferative neoplasms.. International journal of laboratory hematology. :-. 2014
- High incidence of ErbB3, ErbB4, and MET expression in ovarian cancer.. International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists. 33:402-410. 2014
- Narcotic administration and fall-related injury in the hospital: implications for providers and patient safety programs. 2013
- Tyrosine kinome sequencing of pediatric acute lymphoblastic leukemia: a report from the Children's Oncology Group TARGET Project.. Blood. 121:485-488. 2013
- Narcotic administration and fall-related injury in the hospital: implications for patient safety programs and providers.. The International journal of risk & safety in medicine. 25:229-234. 2013
- Gene expression profiles predictive of outcome and age in infant acute lymphoblastic leukemia: a Children's Oncology Group study.. Blood. 119:1872-1881. 2012
- Identification of a small molecule yeast TORC1 inhibitor with a multiplex screen based on flow cytometry.. ACS chemical biology. 7:715-722. 2012
- Outcome modeling with CRLF2, IKZF1, JAK, and minimal residual disease in pediatric acute lymphoblastic leukemia: a Children's Oncology Group study.. Blood. 119:3512-3522. 2012
- Pediatric B-lymphoblastic leukemia with RUNX1 amplification: clinicopathologic study of eight cases.. Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc. 24:1606-1611. 2011
- In utero exposure of female CD-1 mice to AZT and/or 3TC: II. Persistence of functional alterations in cardiac tissue.. Cardiovascular toxicology. 10:87-99. 2010
- Gene expression classifiers for relapse-free survival and minimal residual disease improve risk classification and outcome prediction in pediatric B-precursor acute lymphoblastic leukemia.. Blood. 115:1394-1405. 2010
- Identification of novel cluster groups in pediatric high-risk B-precursor acute lymphoblastic leukemia with gene expression profiling: correlation with genome-wide DNA copy number alterations, clinical characteristics, and outcome.. Blood. 116:4874-4884. 2010
- Method of detection and breast cancer survival disparities in Hispanic women.. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 19:2453-2460. 2010
- Multivitamins, folate, and green vegetables protect against gene promoter methylation in the aerodigestive tract of smokers.. Cancer research. 70:568-574. 2010
- Rearrangement of CRLF2 is associated with mutation of JAK kinases, alteration of IKZF1, Hispanic/Latino ethnicity, and a poor outcome in pediatric B-progenitor acute lymphoblastic leukemia.. Blood. 115:5312-5321. 2010
- Gene expression signatures predictive of early response and outcome in high-risk childhood acute lymphoblastic leukemia: A Children's Oncology Group Study [corrected].. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 26:4376-4384. 2008
- Gene expression overlap affects karyotype prediction in pediatric acute lymphoblastic leukemia.. Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K. 21:1341-1344. 2007
- Gene expression profiling of adult acute myeloid leukemia identifies novel biologic clusters for risk classification and outcome prediction.. Blood. 108:685-696. 2006
- Redesign of an internal medicine ward rotation: operational challenges and outcomes.
Research
research overview
- Dr. Kang’s primary research interest is statistical modeling and data analysis for high dimensional data including gene expression microarray data, SNP data, and next generation sequencing data. He is working with collaborators at the UNM Cancer Center and the Children’s Oncology Group to develop and validate gene expression models used to improve risk classification, and predictions of outcome, therapeutic response, and relapse risk in childhood leukemia. He is a member of the Analytical Translational Genomics Group at UNM Cancer Center where he works on statistical methods for analyzing next generation sequencing data in cancer research. Another area of Dr. Kang’s research is the statistical evaluation of biomedical tests with a focus on the Receiver Operating Characteristic (ROC) curve. He has proposed a new form of ROC curve based on the generalized proportional odds-rate model, which has some advantages over the commonly used binormal form, and has developed the theory for related statistical inference. He is actively working with pathologists to evaluate the biomarkers in hematopathology. Dr. Kang is also interested in statistical applications in cancer epidemiology. He is currently working with epidemiologists to investigate factors related to the disproportionate breast cancer mortality in Hispanic as compared to non-Hispanic white women in New Mexico.
Contact
full name
- Huining Kang
mailing address
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Division of Epidemiology, Biostatistics, and Preventive Medicine, DoIM MSC10-5550, 1 University of New Mexico
Albuquerque, New Mexico 87131
United States of America
fax
- (505) 272-2570