selected publications
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academic article
- Preclinical efficacy of the GPER-selective agonist G-1 in mouse models of obesity and diabetes.. Science translational medicine. 12:-. 2020
- A Selective Ligand for Estrogen Receptor Proteins Discriminates Rapid and Genomic Signaling.. Cell chemical biology. 26:1692-1702.e5. 2019
- Obligatory role for GPER in cardiovascular aging and disease.. Science signaling. 9:-. 2016
- International Union of Basic and Clinical Pharmacology. XCVII. G Protein-Coupled Estrogen Receptor and Its Pharmacologic Modulators.. Pharmacological reviews. 67:505-540. 2015
- G Protein-coupled Estrogen Receptor Protects from Atherosclerosis.. Scientific reports. 4:-. 2014
- GPER-targeted, 99mTc-labeled, nonsteroidal ligands demonstrate selective tumor imaging and in vivo estrogen binding.. Molecular cancer research : MCR. :-. 2014
- G protein-coupled estrogen receptor-selective ligands modulate endometrial tumor growth.. Obstetrics and gynecology international. 2013:-. 2013
- Bradycardic effects mediated by activation of G protein-coupled estrogen receptor (GPER) in rat nucleus ambiguus. 2012
- Mechanisms of G protein-coupled estrogen receptor-mediated spinal nociception.. The journal of pain : official journal of the American Pain Society. 13:742-754. 2012
- Synthesis and characterization of tricarbonyl-Re/Tc(I) chelate probes targeting the G protein-coupled estrogen receptor GPER/GPR30.. PloS one. 7:-. 2012
- GPR30 expression is required for the mineralocorticoid receptor-independent rapid vascular effects of aldosterone.. Hypertension (Dallas, Tex. : 1979). 57:442-451. 2011
- G protein-coupled estrogen receptor 1-mediated effects in the rat myometrium.. American journal of physiology. Cell physiology. 301:C1262-C1269. 2011
- Identification of a GPER/GPR30 antagonist with improved estrogen receptor counterselectivity.. The Journal of steroid biochemistry and molecular biology. 127:358-366. 2011
- Synthesis and characterization of iodinated tetrahydroquinolines targeting the G protein-coupled estrogen receptor GPR30.. Journal of medicinal chemistry. 53:1004-1014. 2010
- Highly efficient synthesis and characterization of the GPR30-selective agonist G-1 and related tetrahydroquinoline analogs.. Organic & biomolecular chemistry. 8:2252-2259. 2010
- Influence of charge on cell permeability and tumor imaging of GPR30-targeted 111in-labeled nonsteroidal imaging agents.. ACS chemical biology. 5:681-690. 2010
- The G protein-coupled receptor GPR30 inhibits proliferation of estrogen receptor-positive breast cancer cells.. Cancer research. 70:1184-1194. 2010
- Discovery of selective probes and antagonists for G-protein-coupled receptors FPR/FPRL1 and GPR30.. Current topics in medicinal chemistry. 9:1227-1236. 2009
- Duplex high-throughput flow cytometry screen identifies two novel formylpeptide receptor family probes.. Cytometry. Part A : the journal of the International Society for Analytical Cytology. 75:253-263. 2009
- Expression of estrogen receptor GPR30 in the rat spinal cord and in autonomic and sensory ganglia. 2009
- In vivo effects of a GPR30 antagonist.. Nature chemical biology. 5:421-427. 2009
- Estrogen signaling through the transmembrane G protein-coupled receptor GPR30.. Annual review of physiology. 70:165-190. 2008
- GPR30: a novel therapeutic target in estrogen-related disease.. Trends in pharmacological sciences. 29:116-123. 2008
- Preclinical development of a neutral, estrogen receptor-targeted, tridentate 99mTc(I)-estradiol-pyridin-2-yl hydrazine derivative for imaging of breast and endometrial cancers.. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 49:978-986. 2008
- The ins and outs of GPR30: a transmembrane estrogen receptor.. The Journal of steroid biochemistry and molecular biology. 109:350-353. 2008
- Synthetic estrogen derivatives demonstrate the functionality of intracellular GPR30.. ACS chemical biology. 2:536-544. 2007
- GPR30: A G protein-coupled receptor for estrogen.. Molecular and cellular endocrinology. 265-266:138-142. 2007
- Linkage effects on binding affinity and activation of GPR30 and estrogen receptors ERalpha/beta with tridentate pyridin-2-yl hydrazine tricarbonyl-Re/(99m)Tc(I) chelates.. Journal of the American Chemical Society. 128:14476-14477. 2006
- Characterization of a radiolabeled small molecule targeting leukocyte function-associated antigen-1 expression in lymphoma and leukemia.. Cancer biotherapy & radiopharmaceuticals. 21:418-426. 2006
- Steroid-binding G-protein-coupled receptors: new drug discovery targets for old ligands.. Expert opinion on drug discovery. 1:137-150. 2006
- Virtual and biomolecular screening converge on a selective agonist for GPR30.. Nature chemical biology. 2:207-212. 2006
- A transmembrane intracellular estrogen receptor mediates rapid cell signaling.. Science (New York, N.Y.). 307:1625-1630. 2005
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document
- Erratum: G Protein-coupled Estrogen Receptor Protects from Atherosclerosis.. Scientific reports. -. 2015