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Lee, Ji-Hyun Director and Professor of Biostatistics, UNM Comprehensive Cancer Center
Positions
- Professor, Department of Internal Medicine
- Accredited Professional Statistician (pStat®) , American Statistical Association 2012 -
- Director of Biostatistics Shared Resource, UNM Comprehensive Cancer Center , Department of Internal Medicine 2014 -
- President, Caucus for Women in Statistics (CWS) 2017
Dr. Ji-Hyun Lee is a Professor in the UNM School of Medicine, Division of Epidemiology, Biostatistics, and Preventive Medicine in the Department of Internal Medicine. She is also the Director of Biostatistics Shared Resource at the UNM Comprehensive Cancer Center (UNMCCC). Dr. Lee has significant expertise in the design and conduct of cancer clinical trials, including early phase clinical trials; in the design of population cohort studies, community-based randomized control trials, and behavioral interventions; and in studies focused on cancer health disparities. To enhance the Resource’s engagement in design, conduct, and oversight of cancer clinical trials at the UNMCCC, she leads the Biostatistics Clinical Trials Group and serves on the UNMCCC Protocol Review and Monitoring Committee (PRMC). She also directs the Resource effort in education, prioritizes and provides biostatistical support to UNMCCC researchers, mentors junior faculty, and oversees biostatistical staff. Dr. Lee is a Certified Professional Statistician through the American Statistical Association (PStat®). Her research area includes: Correlated data analysis, Group/cluster randomized trials; Generalized linear mixed effects models, Cancer research in epidemiology; Health outcomes and behavior research in cancer prevention, and Best statistical practices.
Keywords: Cancer Research, Environmental Health, Longitudinal Data Analysis, Group Randomized Trials, and Best Statistical Practices.
Research Areas
- Affiliation
- Publications
- Research
- Teaching
- Service
- Background
- Contact
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Affiliation
member of
- The International Biometric Society/Western North American Region (WNAR) Member 2014 -
- Caucus for Women in Statistics (CWS) President, 2017 2012 -
- American Statistical Association Member 2003 -
- American Statistical Association (ASA), District 6 Vice Chair 2017 - 2018
has collaborator
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Kinney, Anita Yeomans
Carolyn R. Surface Endowed Chair inCancer Population Sciences
Tenured Professor, Division of Epidemiology, Biostatistics and Preventive Medicine
Department of Internal Medicine and
Associate Director for Cancer Control and Population Sciences
UNM Comprehensive Cancer Center
- Lewis, Johnnye Professor
- Wheeler, Cosette Faculty Member
- Willman, Cheryl Director
Publications
selected publications
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academic article
- The Draft Genome of an Octocoral, Dendronephthya gigantea.. Genome biology and evolution. 11:949-953. 2019
- Outcomes in Women With Cytology Showing Atypical Squamous Cells of Undetermined Significance With vs Without Human Papillomavirus Testing.. JAMA oncology. 3:1327-1334. 2017
- No prognostic value added by vitamin D pathway SNPs to current prognostic system for melanoma survival. 2017
- Mutant-Allele Tumor Heterogeneity Scores Correlate With Risk of Metastases in Colon Cancer.. Clinical colorectal cancer. :-. 2016
- Functional mechanisms underlying pleiotropic risk alleles at the 19p13.1 breast-ovarian cancer susceptibility locus.. Nature communications. 7:-. 2016
- Population-Based Incidence Rates of Cervical Intraepithelial Neoplasia in the Human Papillomavirus Vaccine Era.. JAMA oncology. :-. 2016
- Randomized Noninferiority Trial of Telephone Delivery of BRCA1/2 Genetic Counseling Compared With In-Person Counseling: 1-Year Follow-Up. 2016
- Primary Care Physicians' Adherence to Expert Recommendations for Cervical Cancer Screening and Prevention in the Context of Human Papillomavirus Vaccination.. Sexually transmitted diseases. 43:438-444. 2016
- Subsequent primary malignancies among multiple myeloma patients treated with or without lenalidomide.. Leukemia & lymphoma. :1-9. 2016
- Racial and ethnic differences in patient navigation: Results from the Patient Navigation Research Program.. Cancer. :-. 2016
- Extended Self-Help for Smoking Cessation: A Randomized Controlled Trial. 2016
- Survival disparities of right- and left-sided colon cancer according to stage: a surveillance, epidemiology, and end results analysis. Gastroenterology. 150:S-247-S-247. 2016
- Identification of Anti-CA125 Antibody Responses in Ovarian Cancer Patients by a Novel Deep Sequence-Coupled Biopanning Platform.. Cancer immunology research. :-. 2015
- Impact of patient navigation in eliminating economic disparities in cancer care.. Cancer. :-. 2015
- Use of Adjuvant Cisplatin-Based Versus Carboplatin-Based Chemotherapy in Non-Small-Cell Lung Cancer: Findings From the Florida Initiative for Quality Cancer Care.. Journal of oncology practice / American Society of Clinical Oncology. 11:332-337. 2015
- Relapse-Prevention Booklets as an Adjunct to a Tobacco Quitline: A Randomized Controlled Effectiveness Trial.. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco. :-. 2015
- Acceptance and adherence to chemoprevention among women at increased risk of breast cancer.. Breast (Edinburgh, Scotland). 24:51-56. 2015
- Prospective study of seroreactivity to JC virus T-antigen and risk of colorectal cancers and adenomas.. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 23:2591-2596. 2014
- A randomized clinical trial of self-help intervention for smoking cessation: research design, interventions, and baseline data.. Contemporary clinical trials. 38:284-290. 2014
- Association between IHC and MSI testing to identify mismatch repair-deficient patients with ovarian cancer.. Genetic testing and molecular biomarkers. 18:229-235. 2014
- Changes in the care of non-small-cell lung cancer after audit and feedback: the Florida initiative for quality cancer care.. Journal of oncology practice / American Society of Clinical Oncology. 10:e247-e254. 2014
- Effect of patient navigation on time to diagnostic resolution among patients with colorectal cancer-related abnormalities.. Journal of cancer education : the official journal of the American Association for Cancer Education. 29:144-150. 2014
- Florida Initiative for Quality Cancer Care: improvements on colorectal cancer quality of care indicators during a 3-year interval.. Journal of the American College of Surgeons. 218:16-25.e1-4. 2014
- Florida initiative for quality cancer care: improvements in breast cancer quality indicators during a 3-year interval.. Journal of the American College of Surgeons. 219:638-645.e1. 2014
- Impact of patient navigation on timely cancer care: the Patient Navigation Research Program.. Journal of the National Cancer Institute. 106:-. 2014
- Journal clubs: an educational approach to advance understanding among community partners and academic researchers about CBPR and cancer health disparities.. Journal of cancer education : the official journal of the American Association for Cancer Education. 29:122-128. 2014
- Modes of delivery of genetic testing services and the uptake of cancer risk management strategies in BRCA1 and BRCA2 carriers.. Clinical genetics. 85:49-53. 2014
- Phase II study of pegylated liposomal doxorubicin, low-dose dexamethasone, and lenalidomide in patients with newly diagnosed multiple myeloma.. American journal of hematology. 89:62-67. 2014
- Primary B-cell CNS lymphoma clinicopathologic and treatment outcomes in 89 patients from a single tertiary care center.. International journal of hematology. 99:450-456. 2014
- Serum albumin as a stable predictor of prognosis during initial treatment in patients with diffuse large B cell lymphoma.. Annals of hematology. :-. 2014
- Serum albumin retains independent prognostic significance in diffuse large B-cell lymphoma in the post-rituximab era.. Annals of hematology. 93:1305-1312. 2014
- Analysis of indoleamine 2-3 dioxygenase (IDO1) expression in breast cancer tissue by immunohistochemistry.. Cancer immunology, immunotherapy : CII. 62:829-837. 2013
- Feasibility trial of a Spanish-language multimedia educational intervention.. Clinical trials (London, England). 10:767-774. 2013
- Patient navigation and time to diagnostic resolution: results for a cluster randomized trial evaluating the efficacy of patient navigation among patients with breast cancer screening abnormalities, Tampa, FL. 2013
- Primary care utilization and colorectal cancer incidence and mortality among Medicare beneficiaries: a population-based, case-control study.. Annals of internal medicine. 159:437-446. 2013
- Simultaneous confidence intervals for a success probability and intraclass correlation, with an application to screening mammography.. Biometrical journal. Biometrische Zeitschrift. 55:944-954. 2013
- TP53 suppression promotes erythropoiesis in del(5q) MDS, suggesting a targeted therapeutic strategy in lenalidomide-resistant patients. 2013
- Telomere length and risk of melanoma, squamous cell carcinoma, and basal cell carcinoma.. Cancer epidemiology. 37:434-439. 2013
- The effects of primary care on breast cancer mortality and incidence among Medicare beneficiaries.. Cancer. 119:2964-2972. 2013
- A cluster randomized trial evaluating the efficacy of patient navigation in improving quality of diagnostic care for patients with breast or colorectal cancer abnormalities.. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 21:1664-1672. 2012
- Analysis of overdispersed count data: application to the Human Papillomavirus Infection in Men (HIM) Study. 2012
- Biomarkers of oxidant load and type-specific clearance of prevalent oncogenic human papillomavirus infection: markers of immune response?. International journal of cancer. Journal international du cancer. 131:219-228. 2012
- Circulating biomarkers of iron storage and clearance of incident human papillomavirus infection.. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 21:859-865. 2012
- Cognitive and psychological impact of BRCA genetic counseling in before and after definitive surgery breast cancer patients.. Annals of surgical oncology. 19:4003-4011. 2012
- Effects of a brief multimedia psychoeducational intervention on the attitudes and interest of patients with cancer regarding clinical trial participation: a multicenter randomized controlled trial. 2012
- Evaluating the quality of colorectal cancer care in the state of Florida: results from the Florida Initiative for Quality Cancer Care.. Journal of oncology practice / American Society of Clinical Oncology. 8:239-245. 2012
- Frequency of mutations in mismatch repair genes in a population-based study of women with ovarian cancer.. British journal of cancer. 107:1783-1790. 2012
- Prevalent serum antibody is not a marker of immune protection against acquisition of oncogenic HPV16 in men.. Cancer research. 72:676-685. 2012
- Risk factors for incident condyloma in a multinational cohort of men: the HIM study.. The Journal of infectious diseases. 205:789-793. 2012
- Self-help booklets for preventing postpartum smoking relapse: a randomized trial. 2012
- Uncertainty in the utility of immunohistochemistry in mismatch repair protein expression in epithelial ovarian cancer.. Anticancer research. 32:4963-4969. 2012
- Validation of a radiosensitivity molecular signature in breast cancer.. Clinical cancer research : an official journal of the American Association for Cancer Research. 18:5134-5143. 2012
- A cluster randomized trial of sun protection at elementary schools. Results from year 2. 2011
- Degree of variability in performance on breast cancer quality indicators: findings from the Florida initiative for quality cancer care.. Journal of oncology practice / American Society of Clinical Oncology. 7:247-251. 2011
- Evaluating the quality of psychosocial care in outpatient medical oncology settings using performance indicators.. Psycho-oncology. 20:1221-1227. 2011
- HPV vaccine information-seeking behaviors among US physicians: government, media, or colleagues?. Vaccine. 29:5090-5093. 2011
- Human papillomavirus (HPV) 6, 11, 16, and 18 seroprevalence is associated with sexual practice and age: results from the multinational HPV Infection in Men Study (HIM Study).. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 20:990-1002. 2011
- Incidence and clearance of genital human papillomavirus infection in men (HIM): a cohort study.. Lancet. 377:932-940. 2011
- Incidence and human papillomavirus (HPV) type distribution of genital warts in a multinational cohort of men: the HPV in men study.. The Journal of infectious diseases. 204:1886-1892. 2011
- Increasing cervical cancer screening in a Hispanic migrant farmworker community through faith-based clinical outreach.. Journal of lower genital tract disease. 15:200-204. 2011
- Innovative approaches to reducing cancer health disparities: the Moffitt Cancer Center Patient Navigator Research Program.. Journal of cancer education : the official journal of the American Association for Cancer Education. 26:649-657. 2011
- Missed clinical opportunities: provider recommendations for HPV vaccination for 11-12 year old girls are limited.. Vaccine. 29:8634-8641. 2011
- Primary care utilization and colorectal cancer outcomes among Medicare beneficiaries.. Archives of internal medicine. 171:1747-1757. 2011
- Quality of care in non-small-cell lung cancer: findings from 11 oncology practices in Florida.. Journal of oncology practice / American Society of Clinical Oncology. 7:e25-e31. 2011
- Telomere length in myelodysplastic syndromes.. Leukemia & lymphoma. 52:1528-1536. 2011
- Anti-inflammatory triterpenoid blocks immune suppressive function of MDSCs and improves immune response in cancer.. Clinical cancer research : an official journal of the American Association for Cancer Research. 16:1812-1823. 2010
- Epidemiologic factors associated with seropositivity to human papillomavirus type 16 and 18 virus-like particles and risk of subsequent infection in men.. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 19:511-516. 2010
- Evaluation of phone-based genetic counselling in African American women using culturally tailored visual aids.. Clinical genetics. 78:124-131. 2010
- Exploring disparities and variability in perceptions and self-reported colorectal cancer screening among three ethnic subgroups of U. S. Blacks.. Oncology nursing forum. 37:581-591. 2010
- High risk men's perceptions of pre-implantation genetic diagnosis for hereditary breast and ovarian cancer.. Human reproduction (Oxford, England). 25:2543-2550. 2010
- Strategies for assessing community challenges and strengths for cancer disparities participatory research and outreach. 2010
- Sun protection at elementary schools: a cluster randomized trial.. Journal of the National Cancer Institute. 102:484-492. 2010
- A gene expression model of intrinsic tumor radiosensitivity: prediction of response and prognosis after chemoradiation.. International journal of radiation oncology, biology, physics. 75:489-496. 2009
- Analysis of group randomized trials with multiple binary endpoints and small number of groups. 2009
- Circumcision and sexual behavior: factors independently associated with human papillomavirus detection among men in the HIM study.. International journal of cancer. Journal international du cancer. 124:1251-1257. 2009
- Initial evaluation of quality indicators for psychosocial care of adults with cancer.. Cancer control : journal of the Moffitt Cancer Center. 16:328-334. 2009
- Phase I trial of vorinostat and doxorubicin in solid tumours: histone deacetylase 2 expression as a predictive marker.. British journal of cancer. 101:1044-1050. 2009
- Physician referral for fertility preservation in oncology patients: a national study of practice behaviors. 2009
- Prospective study of JC virus seroreactivity and the development of colorectal cancers and adenomas.. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 18:1515-1523. 2009
- Sampling strategies for tissue microarrays to evaluate biomarkers in ovarian cancer.. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 18:28-34. 2009
- Systems biology modeling of the radiation sensitivity network: a biomarker discovery platform.. International journal of radiation oncology, biology, physics. 75:497-505. 2009
- The Florida Initiative for Quality Cancer Care: a regional project to measure and improve cancer care.. Cancer control : journal of the Moffitt Cancer Center. 16:318-327. 2009
- Age-specific prevalence, incidence, and duration of human papillomavirus infections in a cohort of 290 US men.. The Journal of infectious diseases. 198:827-835. 2008
- Correlates of human papillomavirus viral load with infection site in asymptomatic men.. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 17:3573-3576. 2008
- Phase 2 study of gemcitabine and irinotecan in metastatic breast cancer with correlatives to determine topoisomerase I localization as a predictor of response.. Cancer. 113:2646-2654. 2008
- Phase II trial of B7-1 (CD-86) transduced, cultured autologous tumor cell vaccine plus subcutaneous interleukin-2 for treatment of stage IV renal cell carcinoma.. Journal of immunotherapy (Hagerstown, Md. : 1997). 31:72-80. 2008
- Phenotypic and functional analysis of dendritic cells and clinical outcome in patients with high-risk melanoma treated with adjuvant granulocyte macrophage colony-stimulating factor. 2008
- Signal transduction proteins in tumors from Puerto Rican and Caucasian gastric adenocarcinoma patients: expression differences with potential for specific targeted therapies.. Digestive diseases and sciences. 53:2090-2100. 2008
- The human papillomavirus infection in men study: human papillomavirus prevalence and type distribution among men residing in Brazil, Mexico, and the United States.. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 17:2036-2043. 2008
- An exact test for detecting inconsistency in readers interpretation over time in screening mammograms.. Biometrical journal. Biometrische Zeitschrift. 49:672-681. 2007
- Measuring quality of care in the treatment of colorectal cancer: the moffitt quality practice initiative.. Journal of oncology practice / American Society of Clinical Oncology. 3:60-65. 2007
- Phase I trial of histone deacetylase inhibition by valproic acid followed by the topoisomerase II inhibitor epirubicin in advanced solid tumors: a clinical and translational study. 2007
- The use of GEE for analyzing longitudinal binomial data: a primer using data from a tobacco intervention.. Addictive behaviors. 32:187-193. 2007
- Vascular endothelial growth factor-trap overcomes defects in dendritic cell differentiation but does not improve antigen-specific immune responses.. Clinical cancer research : an official journal of the American Association for Cancer Research. 13:4840-4848. 2007
- Activation of stat3 in primary tumors from high-risk breast cancer patients is associated with elevated levels of activated SRC and survivin expression.. Clinical cancer research : an official journal of the American Association for Cancer Research. 12:20-28. 2006
- Association between polymorphisms in the DNA repair genes XRCC1 and APE1, and the risk of prostate cancer in white and black Americans.. The Journal of urology. 175:108-12; discussion 112. 2006
- Combination of p53 cancer vaccine with chemotherapy in patients with extensive stage small cell lung cancer.. Clinical cancer research : an official journal of the American Association for Cancer Research. 12:878-887. 2006
- Deletion polymorphism of UDP-glucuronosyltransferase 2B17 and risk of prostate cancer in African American and Caucasian men.. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 15:1473-1478. 2006
- Persistent activation of stat3 signaling induces survivin gene expression and confers resistance to apoptosis in human breast cancer cells.. Clinical cancer research : an official journal of the American Association for Cancer Research. 12:11-19. 2006
- Action of the Src family kinase inhibitor, dasatinib (BMS-354825), on human prostate cancer cells.. Cancer research. 65:9185-9189. 2005
- Factors associated with the likelihood of receiving second line therapy for advanced non-small cell lung cancer.. Lung cancer (Amsterdam, Netherlands). 47:253-259. 2005
- Polymorphisms in the promoter region of neutrophil elastase gene and lung cancer risk.. Lung cancer (Amsterdam, Netherlands). 48:315-321. 2005
- Phase II trial of paclitaxel, ifosfamide, and carboplatin in extensive-stage small cell lung cancer.. Lung cancer (Amsterdam, Netherlands). 40:91-97. 2003
- The impact of age on toxicity, response rate, quality of life, and survival in patients with advanced, Stage IIIB or IV nonsmall cell lung carcinoma treated with carboplatin and paclitaxel.. Cancer. 98:779-788. 2003
- Phase III trial comparing a defined duration of therapy versus continuous therapy followed by second-line therapy in advanced-stage IIIB/IV non-small-cell lung cancer.. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 20:1335-1343. 2002
- Second-line, low-dose, weekly paclitaxel in patients with stage IIIB/IV nonsmall cell lung carcinoma who fail first-line chemotherapy with carboplatin plus paclitaxel.. Cancer. 95:1265-1273. 2002
- Assessment of elementary school students' sun protection behaviors.. Pediatric dermatology. 27:182-188.
- Influence of primary care on breast cancer outcomes among Medicare beneficiaries.
- Men's responses to HPV test results: development of a theory-based survey.. American journal of health behavior. 33:728-744.
- Satisfaction with physician recommendation for and information about genetic counseling among breast cancer patients.. The breast journal. 17:79-82.
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article
- Survival disparities of right- and left-sided colon cancer according to stage: a surveillance, epidemiology, and end results analysis. Gastroenterology. 150:S247-S247. 2016
Research
investigator on
- 5P30CA118100-11: P30 UNM Comprehensive Cancer Center Support Grant 2015 - 2020
- U54CA164336:New Mexico HPV Outcomes, Practice Effectiveness and Surveillance (NM-HOPES) 2015 - 2016
- P50 ES026102:Center for Native Environmental Health Equity Research 2016 -
- U19 AI113187-01: Epidemiology and Prevention Interdisciplinary Center (EPIC) for Sexually Transmitted Infections (EPIC-STI) 2015 -
Teaching
teaching overview
- Biostatistics 101 for cancer reserachers at UNM Cancer Center
Service
reviewer of
- PRMC (Protocol) 2014 -
- NASA (Research Proposal) 2013 -
- EDRN (Early Detection Research Network), NCI/NIH. (Research Proposal) 2015
professional service activities
- PLoS One Academic Editor 2014 -
- Caucus for Women in Statistics (CWS) President Elect 2017; Member 2012 -
- The Journal of Midwifery and Women's Health (JMWH) Peer Review Panelist 2008 -
- Medical Problems of Performing Artists (MPPA) Statistical Editor 2007 -
- PLoS One Statistical Advisor 2006 -
Background
education and training
- D.P.H. in Biostatistics, Biostatistics , UNC-CH, Practical Issues Arising in Clustered Data: Modified GEE and Goodness-Of-Fit Test, Overdispersion, and Change-point Models. Advisor: Bahjat F. Qaqish, Ph.D. 2000 - 2003
- M.Sc. in Biostatistics, Biostatistics , UNC-CH 1997 - 2000
Contact
full name
-
Ji-Hyun
Lee, Ms. Connie Volker
Administrative Assistant
Email: cvolker@salud.unm.edu
Phone: 505-272-4180 Fax 505-272-2570
mailing address
-
MSC07 4025, 1 University of New Mexico
Albuquerque, New Mexico 87131-0001
United States of America