publication venue for Aging is associated with dimerization and inactivation of the brain-enriched tyrosine phosphatase STEP.. 41:25-38. 2016 Human tau expression reduces adult neurogenesis in a mouse model of tauopathy.. :-. 2015 IGF-1 signaling reduces neuro-inflammatory response and sensitivity of neurons to MPTP.. 30:2021-2030. 2009