Adolescents have the highest rate of sexually transmitted disease (STD) of any sexually active age group. This article reviews the biological, psychological, and social factors that place adolescents at increased risk for STDs. The major STDs are reviewed, including epidemiology, clinical presentation, methods of diagnosis, and treatment modalities. In addition, major sequelae of STDs--including pelvic inflammatory disease, perihepatitis, Reiter's syndrome, and disseminated gonorrhea infection--are discussed.
