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Publications in VIVO
 

Stuart S. Winter, MD Vice Chair for Pediatric Research

Positions

I am a pediatric hematologist/oncologist with over 20 years experience. My clinical practice revolves around my on-going interests in pediatric cancers and hematological disorders.  Within my division, I play an active role in performing procedures related to my subspecialty, as well as participate in several Philanthropic endeavors, including Health Care Director for our annual Camp Enchantment and other volunteer work for the American Cancer Society.  My area of translational focus is in the study of acute lymphoblastic leukemia (ALL) biology, risk-classification and conduction of clinical trials. In collaboration with several basic cell biologists, I have developed novel insights into the roles played by the bone marrow microenvironment in leukemic cell survival, as well as the molecular mechanisms leading to intrinsic and acquired multi-drug resistance.  

Research Areas

selected publications

research overview

  • My area of translational focus is in the study of acute lymphoblastic leukemia (ALL) biology, risk-classification and conduction of clinical trials. In collaboration with several basic cell biologists, I have developed novel insights into the roles played by the bone marrow microenvironment in leukemic cell survival, as well as the molecular mechanisms leading to intrinsic and acquired multi-drug resistance.  Building on these foundations, I am the Study Chair for a Children’s Oncology Group (COG) T-ALL biology study, “AALL10B1 - Biological Correlates with T-cell Lymphoblastic Leukemia (T-ALL) Gene Expression and Clinical Outcome”, a gene profiling study designed to investigate expression signatures that predict induction failure and relapse after first remission.  This study is linked to “AALL0434 - Intensified Methotrexate, Nelarabine (Compound 506U78; IND # 52611) and Augmented BFM Therapy for Children and Young Adults with Newly Diagnosed T-cell Acute Lymphoblastic Leukemia (ALL) or Lymphoblastic Lymphoma (LL)”, for which I am study Co-Chair. 

eRA Commons id

  • SWINTER