academic article

• Epigenetic silencing of SOCS5 potentiates JAK-STAT signaling and progression of T-cell acute lymphoblastic leukemia..  Cancer Sciecne.  110:1931-1946. 2019
• Leukemia-derived exosomes and cytokines pave the way for entry into the brain..  Journal of leukocyte biology.  105:741-753. 2019
• Hedgehog pathway mutations drive oncogenic transformation in high-risk T-cell acute lymphoblastic leukemia..  Leukemia.  32:2126-2137. 2018
• High-Throughput Flow Cytometry Identifies Small-Molecule Inhibitors for Drug Repurposing in T-ALL..  SLAS Discovery.  23:732-741. 2018
• Severe pegaspargase hypersensitivity reaction rates (grade ≥3) with intravenous infusion vs. intramuscular injection: analysis of 54,280 doses administered to 16,534 patients on children's oncology group (COG) clinical trials..  Leukemia & lymphoma.  59:1624-1633. 2018
• Inclusion of special populations in clinical research: important considerations and guidelines..  Journal of clinical and translational research.  4:56-69. 2018
• Dynamic re-immunization of off-treatment childhood cancer survivors: An implementation feasibility study. 2018
• Dysregulated transcriptional networks in KMT2A- and MLLT10-rearranged T-ALL..  Biomarker research.  6:-. 2018
• Characterization of the anti-CD22 targeted therapy, moxetumomab pasudotox, for B-cell precursor acute lymphoblastic leukemia..  Pediatric blood & cancer.  64:-. 2017
• CARMA1 is a novel regulator of T-ALL disease and leukemic cell migration to the CNS..  Leukemia.  31:255-258. 2017
• Dynamic pre-BCR homodimers fine-tune autonomous survival signals in B cell precursor acute lymphoblastic leukemia..  Science signaling.  9:-. 2016
• Integration of ruxolitinib into dose-intensified therapy targeted against a novel JAK2 F694L mutation in B-precursor acute lymphoblastic leukemia. 2016
• ----Cyclic AMP efflux inhibitors as potential therapeutic agents for leukemia..  Oncotarget.  :-. 2016
• MLL rearrangements impact outcome in HOXA-deregulated T-lineage acute lymphoblastic leukemia: A children's oncology group study..  Leukemia.  :-. 2016
• RasGRP1 overexpression in T-ALL increases basal nucleotide exchange on Ras rendering the Ras/PI3K/Akt pathway responsive to protumorigenic cytokines..  Oncogene.  :-. 2015
• Safe integration of nelarabine into intensive chemotherapy in newly diagnosed T-cell acute lymphoblastic leukemia: Children's Oncology Group Study AALL0434. 2015
• Congenital erythropoietic porphyria linked to GATA1-R216W mutation: challenges for diagnosis. 2015
• The evaluation of thioridazine as a hematopoietic progenitor cell mobilizing agent in healthy human subjects..  Journal of clinical pharmacology.  :-. 2014
• Pyrosequencing for Classification of Human FcγRIIIA Allotypes: A Comparison with PCR-Based Techniques.  Molecular Diagnosis & Therapy.  2014
• Inactivation of the Cdkn2a locus cooperates with HMGA1 to drive T-cell leukemogenesis..  Leukemia & lymphoma.  54:1762-1768. 2013
• ATP Binding Cassette C1 (ABCC1/MRP1)-mediated drug efflux contributes to disease progression in T-lineage acute lymphoblastic leukemia..  Health.  5:-. 2013
• Macrophage and NK-mediated killing of precursor-B acute lymphoblastic leukemia cells targeted with a-fucosylated anti-CD19 humanized antibodies..  Leukemia.  :-. 2013
• High-throughput sequencing detects minimal residual disease in acute T lymphoblastic leukemia..  Science translational medicine.  4:-. 2012
• The genetic basis of early T-cell precursor acute lymphoblastic leukaemia..  Nature.  481:157-163. 2012
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• Drug Repurposing from an Academic Perspective..  Drug discovery today. Therapeutic strategies.  8:61-69. 2011
• Drug Repurposing from an Academic Perspective..  Drug discovery today. Therapeutic strategies.  8:61-69. 2011
• GSI-I (Z-LLNle-CHO) inhibits ?-secretase and the proteosome to trigger cell death in precursor-B acute lymphoblastic leukemia..  Leukemia.  25:1135-1146. 2011
• Is prolonged stem cell mobilization detrimental for hematopoiesis?.  Medical hypotheses.  77:1111-1113. 2011
• Pediatric acute leukemia therapies informed by molecular analysis of high-risk disease..  Hematology / the Education Program of the American Society of Hematology. American Society of Hematology. Education Program.  2011:366-373. 2011
• Recommendations for broader coverage antifungal prophylaxis in childhood acute myeloid leukemia: ASH evidence-based review 2011..  Hematology / the Education Program of the American Society of Hematology. American Society of Hematology. Education Program.  2011:374-376. 2011
• Absence of biallelic TCRgamma deletion predicts early treatment failure in pediatric T-cell acute lymphoblastic leukemia..  Journal of clinical oncology : official journal of the American Society of Clinical Oncology.  28:3816-3823. 2010
• IKK inhibitor bay 11-7082 induces necroptotic cell death in precursor-B acute lymphoblastic leukaemic blasts..  British journal of haematology.  148:487-490. 2010
• Inactivation of LEF1 in T-cell acute lymphoblastic leukemia..  Blood.  115:2845-2851. 2010
• Interconnecting molecular pathways in the pathogenesis and drug sensitivity of T-cell acute lymphoblastic leukemia..  Blood.  115:1735-1745. 2010
• Enhanced leukemia cell detection using a novel magnetic needle and nanoparticles..  Cancer research.  69:8310-8316. 2009
• Differential expression of Ikaros isoforms in monozygotic twins with MLL-rearranged precursor-B acute lymphoblastic leukemia..  Journal of pediatric hematology/oncology.  30:941-944. 2008
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• High-throughput screening for daunorubicin-mediated drug resistance identifies mometasone furoate as a novel ABCB1-reversal agent..  Journal of biomolecular screening.  13:185-193. 2008
• Risk determinants for catheter-associated blood stream infections in children and young adults with cancer. 2008
• Genetic alterations determine chemotherapy resistance in childhood T-ALL: modelling in stage-specific cell lines and correlation with diagnostic patient samples..  British journal of haematology.  139:20-30. 2007
• Identification of genomic classifiers that distinguish induction failure in T-lineage acute lymphoblastic leukemia: a report from the Children's Oncology Group..  Blood.  110:1429-1438. 2007
• Antimetabolite-based therapy in childhood T-cell acute lymphoblastic leukemia: a report of POG study 9296. 2006
• Clinical manifestations of hemoglobin Chico at high altitude..  Journal of pediatric hematology/oncology.  28:760-762. 2006
• Risk for leukemia in infants without Down syndrome who have transient myeloproliferative disorder..  The Journal of pediatrics.  148:687-689. 2006
• Pain and distress from bone marrow aspirations and lumbar punctures..  The Annals of pharmacotherapy.  37:17-22. 2003
• Cellular neurothekeoma of the chest wall..  Medical and pediatric oncology.  39:134-136. 2002
• Hyperammonemia after chemotherapy in an adolescent with hepatocellular carcinoma..  Journal of pediatric gastroenterology and nutrition.  25:537-540. 1997
• Rasburicase for the management of tumor lysis syndrome in neonates..  The Annals of pharmacotherapy.  40:1445-1450.