selected publications
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academic article
- Bevacizumab May Differentially Improve Ovarian Cancer Outcome in Patients with Proliferative and Mesenchymal Molecular Subtypes.. Clinical cancer research : an official journal of the American Association for Cancer Research. 23:3794-3801. 2017
- TP53 mutations, tetraploidy and homologous recombination repair defects in early stage high-grade serous ovarian cancer.. Nucleic acids research. 43:6945-6958. 2015
- PG545 enhances anti-cancer activity of chemotherapy in ovarian models and increases surrogate biomarkers such as VEGF in preclinical and clinical plasma samples.. European journal of cancer (Oxford, England : 1990). 51:879-892. 2015
- Targeting of mutant p53-induced FoxM1 with thiostrepton induces cytotoxicity and enhances carboplatin sensitivity in cancer cells.. Oncotarget. 5:11365-11380. 2014
- Tumor hypomethylation at 6p21.3 associates with longer time to recurrence of high-grade serous epithelial ovarian cancer.. Cancer research. 74:3084-3091. 2014
- Loss of HSulf-1 promotes altered lipid metabolism in ovarian cancer.. Cancer & metabolism. 2:-. 2014
- APOBEC3B upregulation and genomic mutation patterns in serous ovarian carcinoma.. Cancer research. 73:7222-7231. 2013
- Platinum-sensitive recurrence in ovarian cancer: the role of tumor microenvironment.. Frontiers in oncology. 3:-. 2013
- Epigenome-wide ovarian cancer analysis identifies a methylation profile differentiating clear-cell histology with epigenetic silencing of the HERG K+ channel.. Human molecular genetics. 22:3038-3047. 2013
- Metformin intake is associated with better survival in ovarian cancer: a case-control study.. Cancer. 119:555-562. 2013
- Assessment of resistance to anoikis in ovarian cancer.. Methods in molecular biology (Clifton, N.J.). 1049:347-354. 2013
- Network-based survival analysis reveals subnetwork signatures for predicting outcomes of ovarian cancer treatment.. PLoS computational biology. 9:-. 2013
- Role of heparan sulfatases in ovarian and breast cancer.. American journal of cancer research. 3:34-45. 2013
- HtrA1 sensitizes ovarian cancer cells to cisplatin-induced cytotoxicity by targeting XIAP for degradation.. International journal of cancer. Journal international du cancer. 130:1029-1035. 2012
- HSulf-1 modulates FGF2- and hypoxia-mediated migration and invasion of breast cancer cells.. Cancer research. 71:2152-2161. 2011
- Comparison of gene expression patterns between avian and human ovarian cancers.. Gynecologic oncology. 120:256-264. 2011
- Expression and functional significance of HtrA1 loss in endometrial cancer.. Clinical cancer research : an official journal of the American Association for Cancer Research. 17:427-436. 2011
- Minichromosome maintenance protein 7 as a potential prognostic factor for progression-free survival in high-grade serous carcinomas of the ovary.. Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc. 24:277-287. 2011
- Downregulation of HtrA1 promotes resistance to anoikis and peritoneal dissemination of ovarian cancer cells.. Cancer research. 70:3109-3118. 2010
- High temperature requirement A3 (HtrA3) promotes etoposide- and cisplatin-induced cytotoxicity in lung cancer cell lines.. The Journal of biological chemistry. 285:12011-12027. 2010
- Serine protease HtrA1 associates with microtubules and inhibits cell migration.. Molecular and cellular biology. 29:4177-4187. 2009
- Analysis of gene expression in stage I serous tumors identifies critical pathways altered in ovarian cancer.. Gynecologic oncology. 114:3-11. 2009
- HtrA serine proteases as potential therapeutic targets in cancer.. Current cancer drug targets. 9:451-468. 2009
- Identification of tubulins as substrates of serine protease HtrA1 by mixture-based oriented peptide library screening.. Journal of cellular biochemistry. 107:253-263. 2009
- Elevated expression of serine protease HtrA1 in preeclampsia and its role in trophoblast cell migration and invasion.. American journal of obstetrics and gynecology. 199:557.e1-557.10. 2008
- The serine protease HtrA1 is a novel prognostic factor for human mesothelioma.. Pharmacogenomics. 9:1069-1077. 2008
- Molecular pathogenesis and therapeutic targets in epithelial ovarian cancer.. Journal of cellular biochemistry. 102:1117-1129. 2007
- Loss of HSulf-1 expression enhances autocrine signaling mediated by amphiregulin in breast cancer.. The Journal of biological chemistry. 282:14413-14420. 2007
- A variant of the HTRA1 gene increases susceptibility to age-related macular degeneration.. Science (New York, N.Y.). 314:992-993. 2006
- Piroxicam and cisplatin in a mouse model of peritoneal mesothelioma.. Clinical cancer research : an official journal of the American Association for Cancer Research. 12:6133-6143. 2006
- DIXDC1 isoform, l-DIXDC1, is a novel filamentous actin-binding protein.. Biochemical and biophysical research communications. 347:22-30. 2006
- Serine protease HtrA1 modulates chemotherapy-induced cytotoxicity.. The Journal of clinical investigation. 116:1994-2004. 2006
- HSulf-1 inhibits angiogenesis and tumorigenesis in vivo.. Cancer research. 66:6025-6032. 2006
- Heterozygous ATR mutations in mismatch repair-deficient cancer cells have functional significance.. Cancer research. 65:7091-7095. 2005
- Epigenetic silencing of TCEAL7 (Bex4) in ovarian cancer.. Oncogene. 24:5089-5100. 2005
- A candidate tumor suppressor HtrA1 is downregulated in ovarian cancer.. Oncogene. 23:1636-1644. 2004
- HSulf-1 modulates HGF-mediated tumor cell invasion and signaling in head and neck squamous carcinoma.. Oncogene. 23:1439-1447. 2004
- hSulf1 Sulfatase promotes apoptosis of hepatocellular cancer cells by decreasing heparin-binding growth factor signaling.. Gastroenterology. 126:231-248. 2004
- Loss of HSulf-1 up-regulates heparin-binding growth factor signaling in cancer.. The Journal of biological chemistry. 278:23107-23117. 2003
- Identification of underexpressed genes in early- and late-stage primary ovarian tumors by suppression subtraction hybridization.. Cancer research. 62:262-270. 2002