selected publications
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academic article
- Cyclooxygenase-2 haplotypes influence the longitudinal risk of malaria and severe malarial anemia in Kenyan children from a holoendemic transmission region.. Journal of human genetics. :-. 2019
- Genetic variation in interleukin-7 is associated with a reduced erythropoietic response in Kenyan children infected with Plasmodium falciparum.. BMC medical genetics. 20:-. 2019
- Integrated OMICS platforms identify LAIR1 genetic variants as novel predictors of cross-sectional and longitudinal susceptibility to severe malaria and all-cause mortality in Kenyan children.. EBioMedicine. 45:290-302. 2019
- Molecular basis of reduced LAIR1 expression in childhood severe malarial anaemia: Implications for leukocyte inhibitory signalling.. EBioMedicine. 45:278-289. 2019
- Functional haplotypes of Fc gamma (Fc?) receptor (Fc?RIIA and Fc?RIIIB) predict risk to repeated episodes of severe malarial anemia and mortality in Kenyan children.. Human genetics. 131:289-299. 2012
- Functional promoter haplotypes of interleukin-18 condition susceptibility to severe malarial anemia and childhood mortality.. Infection and immunity. 79:4923-4932. 2011
- Polymorphic variability in the 3' untranslated region (UTR) of IL12B is associated with susceptibility to severe anaemia in Kenyan children with acute Plasmodium falciparum malaria.. BMC genetics. 12:-. 2011
- A novel functional variant in the stem cell growth factor promoter protects against severe malarial anemia.. Infection and immunity. 78:453-460. 2010
- Clinical predictors of severe malarial anaemia in a holoendemic Plasmodium falciparum transmission area.. British journal of haematology. 149:711-721. 2010
- Hematological predictors of increased severe anemia in Kenyan children coinfected with Plasmodium falciparum and HIV-1.. American journal of hematology. 85:227-233. 2010
- Haplotypes of IL-10 promoter variants are associated with susceptibility to severe malarial anemia and functional changes in IL-10 production.. Human genetics. 124:515-524. 2008
- Increased circulating interleukin (IL)-23 in children with malarial anemia: in vivo and in vitro relationship with co-regulatory cytokines IL-12 and IL-10.. Clinical immunology (Orlando, Fla.). 126:211-221. 2008
- Polymorphic variability in the interleukin (IL)-1beta promoter conditions susceptibility to severe malarial anemia and functional changes in IL-1beta production.. The Journal of infectious diseases. 198:1219-1226. 2008
- Role of monocyte-acquired hemozoin in suppression of macrophage migration inhibitory factor in children with severe malarial anemia.. Infection and immunity. 75:201-210. 2007
- Acquisition of hemozoin by monocytes down-regulates interleukin-12 p40 (IL-12p40) transcripts and circulating IL-12p70 through an IL-10-dependent mechanism: in vivo and in vitro findings in severe malarial anemia.. Infection and immunity. 74:5249-5260. 2006
- Association of FCgamma receptor IIA (CD32) polymorphism with malarial anemia and high-density parasitemia in infants and young children.. The American journal of tropical medicine and hygiene. 74:573-577. 2006
- Increased severe anemia in HIV-1-exposed and HIV-1-positive infants and children during acute malaria.. AIDS (London, England). 20:275-280. 2006
- Parasitemia, anemia, and malarial anemia in infants and young children in a rural holoendemic Plasmodium falciparum transmission area.. The American journal of tropical medicine and hygiene. 74:376-385. 2006
- Suppression of RANTES in children with Plasmodium falciparum malaria.. Haematologica. 91:1396-1399. 2006
- MIF (macrophage migration inhibitory factor) promoter polymorphisms and susceptibility to severe malarial anemia.. The Journal of infectious diseases. 200:629-637.
- Naturally acquired hemozoin by monocytes promotes suppression of RANTES in children with malarial anemia through an IL-10-dependent mechanism.. Microbes and infection / Institut Pasteur. 11:811-819.
- Suppression of a novel hematopoietic mediator in children with severe malarial anemia.. Infection and immunity. 77:3864-3871.