selected publications
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academic article
- TIGA: Target illumination GWAS analytics.. Bioinformatics (Oxford, England). :-. 2021
- Activation of Rho Family GTPases by Small Molecules.. ACS chemical biology. 13:1514-1524. 2018
- High-Throughput Flow Cytometry Identifies Small-Molecule Inhibitors for Drug Repurposing in T-ALL.. SLAS Discovery. 23:732-741. 2018
- Pharos: Collating protein information to shed light on the druggable genome.. Nucleic acids research. 45:D995-D1002. 2017
- Inhibition of Dihydroorotate Dehydrogenase Overcomes Differentiation Blockade in Acute Myeloid Leukemia. 2016
- Discovery of Small-Molecule Nonfluorescent Inhibitors of Fluorogen-Fluorogen Activating Protein Binding Pair.. Journal of biomolecular screening. :-. 2015
- A Pan-GTPase Inhibitor as a Molecular Probe. 2015
- FRET detection of lymphocyte function-associated antigen-1 conformational extension.. Molecular biology of the cell. 26:43-54. 2015
- Novel Activities of Select NSAID R-Enantiomers against Rac1 and Cdc42 GTPases. 2015
- Pharmaceutical screen identifies novel target processes for activation of autophagy with a broad translational potential.. Nature communications. 6:-. 2015
- An automated high-throughput cell-based multiplexed flow cytometry assay to identify novel compounds to target Candida albicans virulence-related proteins. 2014
- An Overview of the Challenges in Designing, Integrating, and Delivering BARD: A Public Chemical-Biology Resource and Query Portal for Multiple Organizations, Locations, and Disciplines.. Journal of biomolecular screening. :-. 2013
- Characterization of a Cdc42 GTPase Inhibitor and its Use as a Molecular Probe.. The Journal of biological chemistry. :8531. 2013
- Characterization of a Cdc42 protein inhibitor and its use as a molecular probe. 2013
- Fluorescent substrates for flow cytometric evaluation of efflux inhibition in ABCB1, ABCC1, and ABCG2 transporters.. Analytical biochemistry. 437:77-87. 2013
- A competitive nucleotide binding inhibitor: in vitro characterization of Rab7 GTPase inhibition.. ACS chemical biology. 7:1095-1108. 2012
- A competitive nucleotide binding inhibitor: in vitro characterization of Rab7 GTPase inhibition.. ACS chemical biology. 7:1095-1108. 2012
- A Selective ATP-Binding Cassette Subfamily G Member 2 Efflux Inhibitor Revealed via High-Throughput Flow Cytometry.. Journal of biomolecular screening. :-. 2012
- A novel flow cytometric HTS assay reveals functional modulators of ATP binding cassette transporter ABCB6.. PloS one. 7:-. 2012
- Identification of a small molecule yeast TORC1 inhibitor with a multiplex screen based on flow cytometry.. ACS chemical biology. 7:715-722. 2012
- Drug Repurposing from an Academic Perspective.. Drug discovery today. Therapeutic strategies. 8:61-69. 2011
- Drug Repurposing from an Academic Perspective.. Drug discovery today. Therapeutic strategies. 8:61-69. 2011
- Drug Repurposing from an Academic Perspective.. Drug discovery today. Therapeutic strategies. 8:61-69. 2011
- Real-time analysis of the inside-out regulation of lymphocyte function-associated antigen-1 revealed similarities to and differences from very late antigen-4.. The Journal of biological chemistry. 286:20375-20386. 2011
- Simultaneous in vitro molecular screening of protein-peptide interactions by flow cytometry, using six Bcl-2 family proteins as examples.. Nature protocols. 6:943-952. 2011
- A small molecule pan-inhibitor of Ras-superfamily GTPases with high efficacy towards Rab7 2010
- Identification of a small GTPase inhibitor using a high-throughput flow cytometry bead-based multiplex assay.. Journal of biomolecular screening. 15:10-20. 2010
- Identification of inhibitors of vacuolar proton-translocating ATPase pumps in yeast by high-throughput screening flow cytometry.. Analytical biochemistry. 398:203-211. 2010
- Profiling a Selective Probe for RTG Branch of Yeast TORC1 Signaling Pathway 2010
- Selective Efflux Inhibition of ATP-binding Cassette Sub-family G Member 2 2010
- Detection of intracellular granularity induction in prostate cancer cell lines by small molecules using the HyperCyt high-throughput flow cytometry system.. Journal of biomolecular screening. 14:596-609. 2009
- Detection of intracellular granularity induction in prostate cancer cell lines by small molecules using the HyperCyt high-throughput flow cytometry system.. Journal of biomolecular screening. 14:596-609. 2009
- Detection of intracellular granularity induction in prostate cancer cell lines by small molecules using the HyperCyt high-throughput flow cytometry system.. Journal of biomolecular screening. 14:596-609. 2009
- Detection of intracellular granularity induction in prostate cancer cell lines by small molecules using the HyperCyt high-throughput flow cytometry system.. Journal of biomolecular screening. 14:596-609. 2009
- Conformational mAb as a tool for integrin ligand discovery.. Assay and drug development technologies. 7:507-515. 2009
- Real-time analysis of conformation-sensitive antibody binding provides new insights into integrin conformational regulation.. The Journal of biological chemistry. 284:14337-14346. 2009
- Some mechanistic insights into GPCR activation from detergent-solubilized ternary complexes on beads.. Advances in protein chemistry. 74:95-135. 2007
- Glutathione-S-transferase-green fluorescent protein fusion protein reveals slow dissociation from high site density beads and measures free GSH.. Cytometry. Part A : the journal of the International Society for Analytical Cytology. 69:326-334. 2006
- Techniques: GPCR assembly, pharmacology and screening by flow cytometry.. Trends in pharmacological sciences. 25:663-669. 2004
- Real-time analysis of ternary complex on particles: direct evidence for partial agonism at the agonist-receptor-G protein complex assembly step of signal transduction. 2004
- An investigation of liquid carryover and sample residual for a high-throughput flow cytometer sample delivery system.. Analytical chemistry. 76:3810-3817. 2004
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