academic article

• Epigenetic silencing of SOCS5 potentiates JAK-STAT signaling and progression of T-cell acute lymphoblastic leukemia..  Cancer Sciecne.  110:1931-1946. 2019
• Hedgehog pathway mutations drive oncogenic transformation in high-risk T-cell acute lymphoblastic leukemia..  Leukemia.  32:2126-2137. 2018
• High-Throughput Flow Cytometry Identifies Small-Molecule Inhibitors for Drug Repurposing in T-ALL..  SLAS Discovery.  23:732-741. 2018
• Severe pegaspargase hypersensitivity reaction rates (grade ≥3) with intravenous infusion vs. intramuscular injection: analysis of 54,280 doses administered to 16,534 patients on children's oncology group (COG) clinical trials..  Leukemia & lymphoma.  59:1624-1633. 2018
• Antenatal vaccination against Group B streptococcus: attitudes of pregnant women and healthcare professionals in the UK towards participation in clinical trials and routine implementation..  Acta obstetricia et gynecologica Scandinavica.  97:330-340. 2018
• Dysregulated transcriptional networks in KMT2A- and MLLT10-rearranged T-ALL..  Biomarker research.  6:-. 2018
• Potent efficacy of combined PI3K/mTOR and JAK or ABL inhibition in murine xenograft models of Ph-like acute lymphoblastic leukemia..  Blood.  129:177-187. 2017
• Deregulation of DUX4 and ERG in acute lymphoblastic leukemia. 2016
• Genomic analyses identify recurrent MEF2D fusions in acute lymphoblastic leukaemia..  Nature communications.  7:-. 2016
• Characterization of leukemias with ETV6-ABL1 fusion..  Haematologica.  101:1082-1093. 2016
• Biologic and clinical characteristics of adolescent and young adult cancers: Acute lymphoblastic leukemia, colorectal cancer, breast cancer, melanoma, and sarcoma..  Cancer.  122:1017-1028. 2016
• MLL rearrangements impact outcome in HOXA-deregulated T-lineage acute lymphoblastic leukemia: A children's oncology group study..  Leukemia.  :-. 2016
• Truncating Erythropoietin Receptor Rearrangements in Acute Lymphoblastic Leukemia..  Cancer cell.  29:186-200. 2016
• Safe integration of nelarabine into intensive chemotherapy in newly diagnosed T-cell acute lymphoblastic leukemia: Children's Oncology Group Study AALL0434. 2015
• Prognostic significance of minimal residual disease in high risk B-ALL: a report from Children's Oncology Group study AALL0232..  Blood.  :-. 2015
• Signalling thresholds and negative B-cell selection in acute lymphoblastic leukaemia..  Nature.  521:357-361. 2015
• Evaluation of the In Vitro and In Vivo Efficacy of the JAK Inhibitor AZD1480 against JAK-Mutated Acute Lymphoblastic Leukemia..  Molecular cancer therapeutics.  14:364-374. 2015
• A genome-wide association study of susceptibility to acute lymphoblastic leukemia in adolescents and young adults. 2015
• Rise and fall of subclones from diagnosis to relapse in pediatric B-acute lymphoblastic leukaemia..  Nature communications.  6:-. 2015
• Targetable kinase-activating lesions in Ph-like acute lymphoblastic leukemia. 2014
• Tyrosine kinome sequencing of pediatric acute lymphoblastic leukemia: a report from the Children's Oncology Group TARGET Project..  Blood.  121:485-488. 2013
• ARID5B genetic polymorphisms contribute to racial disparities in the incidence and treatment outcome of childhood acute lymphoblastic leukemia..  Journal of clinical oncology : official journal of the American Society of Clinical Oncology.  30:751-757. 2012
• Aberrant STAT5 and PI3K/mTOR pathway signaling occurs in human CRLF2-rearranged B-precursor acute lymphoblastic leukemia..  Blood.  120:833-842. 2012
• Gene expression profiles predictive of outcome and age in infant acute lymphoblastic leukemia: a Children's Oncology Group study..  Blood.  119:1872-1881. 2012
• Genetic alterations activating kinase and cytokine receptor signaling in high-risk acute lymphoblastic leukemia..  Cancer cell.  22:153-166. 2012
• Genome-wide association study identifies germline polymorphisms associated with relapse of childhood acute lymphoblastic leukemia..  Blood.  120:4197-4204. 2012
• Outcome modeling with CRLF2, IKZF1, JAK, and minimal residual disease in pediatric acute lymphoblastic leukemia: a Children's Oncology Group study..  Blood.  119:3512-3522. 2012
• Targeting JAK1/2 and mTOR in murine xenograft models of Ph-like acute lymphoblastic leukemia..  Blood.  120:3510-3518. 2012
• The genetic basis of early T-cell precursor acute lymphoblastic leukaemia..  Nature.  481:157-163. 2012
• Ancestry and pharmacogenomics of relapse in acute lymphoblastic leukemia..  Nature genetics.  43:237-241. 2011
• GSI-I (Z-LLNle-CHO) inhibits ?-secretase and the proteosome to trigger cell death in precursor-B acute lymphoblastic leukemia..  Leukemia.  25:1135-1146. 2011
• Key pathways are frequently mutated in high-risk childhood acute lymphoblastic leukemia: a report from the Children's Oncology Group..  Blood.  118:3080-3087. 2011
• Absence of biallelic TCRgamma deletion predicts early treatment failure in pediatric T-cell acute lymphoblastic leukemia..  Journal of clinical oncology : official journal of the American Society of Clinical Oncology.  28:3816-3823. 2010
• Gene expression classifiers for relapse-free survival and minimal residual disease improve risk classification and outcome prediction in pediatric B-precursor acute lymphoblastic leukemia..  Blood.  115:1394-1405. 2010
• Identification of novel cluster groups in pediatric high-risk B-precursor acute lymphoblastic leukemia with gene expression profiling: correlation with genome-wide DNA copy number alterations, clinical characteristics, and outcome..  Blood.  116:4874-4884. 2010
• Inactivation of LEF1 in T-cell acute lymphoblastic leukemia..  Blood.  115:2845-2851. 2010
• Rearrangement of CRLF2 is associated with mutation of JAK kinases, alteration of IKZF1, Hispanic/Latino ethnicity, and a poor outcome in pediatric B-progenitor acute lymphoblastic leukemia..  Blood.  115:5312-5321. 2010
• Deletion of IKZF1 and prognosis in acute lymphoblastic leukemia..  The New England journal of medicine.  360:470-480. 2009
• Genome-wide interrogation of germline genetic variation associated with treatment response in childhood acute lymphoblastic leukemia..  JAMA.  301:393-403. 2009
• Germline genomic variants associated with childhood acute lymphoblastic leukemia..  Nature genetics.  41:1001-1005. 2009
• JAK mutations in high-risk childhood acute lymphoblastic leukemia..  Proceedings of the National Academy of Sciences of the United States of America.  106:9414-9418. 2009
• Rearrangement of CRLF2 in B-progenitor- and Down syndrome-associated acute lymphoblastic leukemia..  Nature genetics.  41:1243-1246. 2009
• Gene expression signatures predictive of early response and outcome in high-risk childhood acute lymphoblastic leukemia: A Children's Oncology Group Study [corrected]..  Journal of clinical oncology : official journal of the American Society of Clinical Oncology.  26:4376-4384. 2008
• Resolution of ambiguous low-level positive quantitative polymerase chain reaction results in TEL-AML1 positive ALL using a post-PCR fluorescent oligoligation method..  British journal of haematology.  135:358-361. 2006