has collaborator
- Wandinger-Ness, Angela Professor
- Contact Info
- (505) 272-1333
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Cook, Linda Professor
Positions
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- Research
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Affiliation
Publications
selected publications
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academic article
- Contemporary clinical isolates of Staphylococcus aureus from pediatric osteomyelitis patients display unique characteristics in a mouse model of hematogenous osteomyelitis.. Infection and immunity. :-. 2021
- New Mexico Female Miners Have Lower Odds for COPD than Their Male Counterparts.. COPD. :1-6. 2020
- Case-control study of endogenous sex steroid hormones and risk of endometrial cancer.. Cancer causes & control : CCC. 31:161-171. 2020
- A combination of the immunohistochemical markers CK7 and SATB2 is highly sensitive and specific for distinguishing primary ovarian mucinous tumors from colorectal and appendiceal metastases.. Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc. 32:1834-1846. 2019
- A comprehensive gene-environment interaction analysis in Ovarian Cancer using genome-wide significant common variants.. International journal of cancer. 144:2192-2205. 2019
- Genetic Data from Nearly 63,000 Women of European Descent Predicts DNA Methylation Biomarkers and Epithelial Ovarian Cancer Risk.. Cancer research. 79:505-517. 2019
- Greater Odds for Angina in Uranium Miners Than Nonuranium Miners in New Mexico.. Journal of occupational and environmental medicine. 61:1-7. 2019
- Recent Use of Oral Contraceptives and Risk of Luminal B, Triple-Negative, and HER2-Overexpressing Breast Cancer.. Hormones & cancer. 10:71-76. 2019
- Relationship between Diabetes and Diabetes Medications and Risk of Different Molecular Subtypes of Breast Cancer.. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 28:1802-1808. 2019
- Dual Actions of Ketorolac in Metastatic Ovarian Cancer.. Cancers. 11:-. 2019
- Ovarian Carcinoma Histotype: Strengths and Limitations of Integrating Morphology With Immunohistochemical Predictions.. International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists. 38:353-362. 2019
- Among All Miners, Coal Miners Demonstrate a Disproportionately High Prevalence of Obstructive Spirometric Abnormality and Chronic Bronchitis.. Journal of occupational and environmental medicine. 61:328-334. 2019
- Greater Odds for Angina in Uranium Miners than Non-uranium Miners in New Mexico.. Journal of occupational and environmental medicine. :-. 2018
- Dose-Response Association of CD8+ Tumor-Infiltrating Lymphocytes and Survival Time in High-Grade Serous Ovarian Cancer. 2017
- Combined oral contraceptive use before the first birth and epithelial ovarian cancer risk.. British journal of cancer. 116:265-269. 2017
- Enrichment of putative PAX8 target genes at serous epithelial ovarian cancer susceptibility loci.. British journal of cancer. 116:524-535. 2017
- PALB2, CHEK2 and ATM rare variants and cancer risk: data from COGS.. Journal of medical genetics. 53:800-811. 2016
- Association of vitamin D levels and risk of ovarian cancer: a Mendelian randomization study.. International journal of epidemiology. 45:1619-1630. 2016
- Functional mechanisms underlying pleiotropic risk alleles at the 19p13.1 breast-ovarian cancer susceptibility locus.. Nature communications. 7:-. 2016
- Assessing the genetic architecture of epithelial ovarian cancer histological subtypes.. Human genetics. 135:741-756. 2016
- Genome-Wide Meta-Analyses of Breast, Ovarian, and Prostate Cancer Association Studies Identify Multiple New Susceptibility Loci Shared by at Least Two Cancer Types.. Cancer discovery. :-. 2016
- Reproductive factors and risk of luminal, HER2-overexpressing and triple negative breast cancer among multiethnic women.. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. :-. 2016
- Body mass index and risk of luminal, HER2-overexpressing, and triple negative breast cancer.. Breast cancer research and treatment. :-. 2016
- GWAS meta-analysis of 16,852 women identifies new susceptibility locus for endometrial cancer.. Human molecular genetics. :-. 2016
- Mortality risk from comorbidities independent of triple-negative breast cancer status: NCI-SEER-based cohort analysis. 2016
- A targeted genetic association study of epithelial ovarian cancer susceptibility.. Oncotarget. 7:7381-7389. 2016
- Adult lifetime alcohol consumption and invasive epithelial ovarian cancer risk in a population-based case-control study.. Gynecologic oncology. 140:277-284. 2016
- An Innovative Approach to Enhancing Access to Medical Screening for Miners using a Mobile Clinic with Telemedicine Capability. 2016
- Female chromosome X mosaicism is age-related and preferentially affects the inactivated X chromosome.. Nature communications. 7:-. 2016
- Uranium Workers Demonstrate Lower Lobe Predominant Irregular Pneumoconiotic Opacities on Chest Radiographs. 2016
- Epithelial-Mesenchymal Transition (EMT) Gene Variants and Epithelial Ovarian Cancer (EOC) Risk.. Genetic epidemiology. :-. 2015
- Network-based integration of GWAS and gene expression identifies a HOX-centric network associated with serous ovarian cancer risk.. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. :-. 2015
- Shared genetics underlying epidemiological association between endometriosis and ovarian cancer.. Human molecular genetics. :-. 2015
- A novel pharmacologic activity of ketorolac for therapeutic benefit in ovarian cancer patients.. Clinical cancer research : an official journal of the American Association for Cancer Research. :-. 2015
- Chemotherapy Response Score: Development and Validation of a System to Quantify Histopathologic Response to Neoadjuvant Chemotherapy in Tubo-Ovarian High-Grade Serous Carcinoma. 2015
- Morphologic and Molecular Characteristics of Mixed Epithelial Ovarian Cancers.. The American journal of surgical pathology. :-. 2015
- Glycemic load and endometrial cancer risk in a case-control study of Canadian women.. Cancer epidemiology. 39:170-173. 2015
- Characterization of large structural genetic mosaicism in human autosomes.. American journal of human genetics. 96:487-497. 2015
- Evaluating the ovarian cancer gonadotropin hypothesis: A candidate gene study.. Gynecologic oncology. 136:542-548. 2015
- Infertility and incident endometrial cancer risk: a pooled analysis from the epidemiology of endometrial cancer consortium (E2C2).. British journal of cancer. 112:925-933. 2015
- Identification of six new susceptibility loci for invasive epithelial ovarian cancer. 2015
- Body Mass Index Genetic Risk Score and Endometrial Cancer Risk. 2015
- Cis-eQTL analysis and functional validation of candidate susceptibility genes for high-grade serous ovarian cancer.. Nature communications. 6:-. 2015
- Common Genetic Variation In Cellular Transport Genes and Epithelial Ovarian Cancer (EOC) Risk. 2015
- The Breast Cancer to Bone (B2B) Metastases Research Program: a multi-disciplinary investigation of bone metastases from breast cancer.. BMC cancer. 15:-. 2015
- Reliability of self-reported sun exposure in Canadian women and estimation of lifetime exposure to vitamin D from sun and diet.. Public health nutrition. 17:747-755. 2014
- Hormone contraception before the first birth and endometrial cancer risk.. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 23:356-361. 2014
- Exome-wide association study of endometrial cancer in a multiethnic population. 2014
- Longitudinal changes in IGF-I and IGFBP-3, and mammographic density among postmenopausal women.. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 22:2116-2120. 2013
- Endometrial cancer and a family history of cancer.. Gynecologic oncology. 130:334-339. 2013
- Comorbidities and endometrial cancer survival in Hispanics and non-Hispanic whites. 2013
- A review of cancer in U.S. Hispanic populations.. Cancer prevention research (Philadelphia, Pa.). 5:150-163. 2012
- The impact of race and comorbidity on survival in endometrial cancer.. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 21:753-760. 2012
- Carotid intima-media thickness determined vascular age and the Framingham Risk Score.. Critical pathways in cardiology. 10:173-179. 2011
- Case-control study of the metabolic syndrome and metabolic risk factors for endometrial cancer.. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 20:2384-2395. 2011
- Functional polymorphisms in the TERT promoter are associated with risk of serous epithelial ovarian and breast cancers.. PloS one. 6:-. 2011
- A cross-sectional study of intima-media thickness, ethnicity, metabolic syndrome, and cardiovascular risk in 2268 study participants.. Mayo Clinic proceedings. Mayo Clinic. 84:221-228. 2009
- Aberrant promoter methylation in bronchial epithelium and sputum from current and former smokers. 2002
- Post-1971 Era Uranium Workers in New Mexico Have Significant Lung Disease Burden.. Annals of the American Thoracic Society. 515-518. 2019
- No clinical utility of KRAS variant rs61764370 for ovarian or breast cancer.. Gynecologic oncology. -. 2015
Research
research overview
- Dr. Cook is currently working on female hormonally-related cancers, namely ovarian, endometrial and breast cancer. Dr. Cook is the PI of a large National Institutes of Health multi-year grant investigating the mitochondrial DNA differences in several hundred women with and without ovarian cancer with her colleagues at UNM and in Canada. These genetic differences in the mitochondrial DNA could provide the basis for a screening test or possibly even a drug intervention. Other investigations using this resource include candidate SNP studies and novel risk factors for ovarian cancer (vitamin D/sunlight and herbicide exposures). She is also active in the international Ovarian Cancer Association Consortium (OCAC). Dr. Cook has completed an endometrial cancer tissue study and is currently investigating risk factors in women with microsatellite stable and microsatellite instable endometrial cancer. She is also investigating the underlying reasons for survival differences in Hispanic whites and non-Hispanic whites following an endometrial cancer diagnosis. She is a member of the international Epidemiology of Endometrial Cancer Consortium (E2C2). She is also the UNM PI on two projects in a NIH P50 grant with the Fred Hutchinson Cancer Research Center in Seattle, WA. The goal of this P50 project is to investigate and reduce breast cancer disparities between Hispanic and non-Hispanic white women. She is particularly interested in the investigation of the occurrence and the subtypes of the aggressive forms of breast cancer in Hispanic women. Dr. Cook is also interested in developing a molecular epidemiology graduate training program at UNM.
Contact
full name
- Linda S Cook
mailing address
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Division of Epidemiology, Biostatistics, and Preventive Medicine, DoIM MSC10-5550, 1 University of New Mexico
Albuquerque, New Mexico 87131
United States of America
fax
- (505) 272-2570