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Publications in VIVO
 

Bradfute, Steven B Assistant Professor

Positions

Steven B. Bradfute, Ph.D., is an Assistant Professor in the UNM Center for Global Health and Department of Internal Medicine.  Dr. Bradfute received his Ph.D. in Immunology from Baylor College of Medicine (2005) and did a postdoctoral fellowship at the U.S. Army Medical Research Institute of Infectious Diseases (USAMRIID), where he studied immune responses to hemorrhagic fever viruses (HFVs).  HFVs are dangerous pathogens that include filoviruses (Ebola and Marburg) and arenaviruses (such as Junín, Machupo, and Chapare viruses).  HFVs can cause severe disease in humans, and there have been increases in HFV prevalence and geographical spread in recent years.  As there are few treatments or vaccines available for many of these viruses, Dr. Bradfute is​ interested in basic immunology and vaccine development for HFVs.  Current projects in the lab include development and testing of vaccines that generate cross-reactive immune responses against multiple HFVs, and determination of the mechanisms of immunity of efficacious HFV vaccines.  He has existing collaborations with researchers at USAMRIID, the Los Alamos National Laboratory, and the National Institutes of Health. 

selected publications

research overview

  • My work has focused on how hemorrhagic fever viruses (HFVs) bypass immune responses, and development of vaccines for HFVs.  HFVs are dangerous pathogens that include filoviruses (Ebola and Marburg) and arenaviruses (such as Junín, Machupo, and Chapare viruses). Currently, we are working on improving existing Ebola and Marburg virus vaccines by modifying the viral glycoproteins to induce more effective immune responses.  Other projects in the lab include development and testing of vaccines that generate cross-reactive immune responses against multiple HFVs, and determination of the mechanisms of immunity of efficacious HFV vaccines.  

teaching overview

  • *Tutorial leader for Infectious Disease block for Medical Students
    *Lecturer (Host-Pathogen Interactions) for Infectious Disease block for Medical Students
    *Tutorial leader for Immunology block for Medical Students