selected publications
-
academic article
- Suppressed circulating bicyclo-PGE2 levels and leukocyte COX-2 transcripts in children co-infected with P. falciparum malaria and HIV-1 or bacteremia.. Biochemical and biophysical research communications. 436:585-590. 2013
- Feedback-based, system-level properties of vertebrate-microbial interactions. 2013
- Connecting network properties of rapidly disseminating epizoonotics. 2012
- Functional haplotypes of Fc gamma (Fc?) receptor (Fc?RIIA and Fc?RIIIB) predict risk to repeated episodes of severe malarial anemia and mortality in Kenyan children.. Human genetics. 131:289-299. 2012
- Reduced interferon (IFN)-? conditioned by IFNA2 (-173) and IFNA8 (-884) haplotypes is associated with enhanced susceptibility to severe malarial anemia and longitudinal all-cause mortality.. Human genetics. 131:1375-1391. 2012
- Reduced systemic bicyclo-prostaglandin-E2 and cyclooxygenase-2 gene expression are associated with inefficient erythropoiesis and enhanced uptake of monocytic hemozoin in children with severe malarial anemia.. American journal of hematology. 87:782-789. 2012
- Relationship between inflammatory mediator patterns and anemia in HIV-1 positive and exposed children with Plasmodium falciparum malaria.. American journal of hematology. 87:652-658. 2012
- Functional promoter haplotypes of interleukin-18 condition susceptibility to severe malarial anemia and childhood mortality.. Infection and immunity. 79:4923-4932. 2011
- Identification of inflammatory biomarkers for pediatric malarial anemia severity using novel statistical methods.. Infection and immunity. 79:4674-4680. 2011
- Polymorphic variability in the 3' untranslated region (UTR) of IL12B is associated with susceptibility to severe anaemia in Kenyan children with acute Plasmodium falciparum malaria.. BMC genetics. 12:-. 2011
- Severe malarial anemia: innate immunity and pathogenesis.. International journal of biological sciences. 7:1427-1442. 2011
- A novel functional variant in the stem cell growth factor promoter protects against severe malarial anemia.. Infection and immunity. 78:453-460. 2010
- Clinical predictors of severe malarial anaemia in a holoendemic Plasmodium falciparum transmission area.. British journal of haematology. 149:711-721. 2010
- Hematological predictors of increased severe anemia in Kenyan children coinfected with Plasmodium falciparum and HIV-1.. American journal of hematology. 85:227-233. 2010
- Haplotypes of IL-10 promoter variants are associated with susceptibility to severe malarial anemia and functional changes in IL-10 production.. Human genetics. 124:515-524. 2008
- Increased circulating interleukin (IL)-23 in children with malarial anemia: in vivo and in vitro relationship with co-regulatory cytokines IL-12 and IL-10.. Clinical immunology (Orlando, Fla.). 126:211-221. 2008
- Higher production of peripheral blood macrophage migration inhibitory factor in healthy children with a history of mild malaria relative to children with a history of severe malaria.. The American journal of tropical medicine and hygiene. 76:1033-1036. 2007
- Role of monocyte-acquired hemozoin in suppression of macrophage migration inhibitory factor in children with severe malarial anemia.. Infection and immunity. 75:201-210. 2007
- Acquisition of hemozoin by monocytes down-regulates interleukin-12 p40 (IL-12p40) transcripts and circulating IL-12p70 through an IL-10-dependent mechanism: in vivo and in vitro findings in severe malarial anemia.. Infection and immunity. 74:5249-5260. 2006
- Decreased circulating macrophage migration inhibitory factor (MIF) protein and blood mononuclear cell MIF transcripts in children with Plasmodium falciparum malaria.. Clinical immunology (Orlando, Fla.). 119:219-225. 2006
- Suppression of RANTES in children with Plasmodium falciparum malaria.. Haematologica. 91:1396-1399. 2006
- Suppression of prostaglandin E2 by malaria parasite products and antipyretics promotes overproduction of tumor necrosis factor-alpha: association with the pathogenesis of childhood malarial anemia.. The Journal of infectious diseases. 193:1384-1393. 2006
- Differential regulation of beta-chemokines in children with Plasmodium falciparum malaria.. Infection and immunity. 73:4190-4197. 2005
- Impaired systemic production of prostaglandin E2 in children with cerebral malaria.. The Journal of infectious diseases. 191:1548-1557. 2005
- Stage-specific effects of Plasmodium falciparum-derived hemozoin on blood mononuclear cell TNF-alpha regulation and viral replication.. AIDS (London, England). 19:1771-1780. 2005
- Elevated nitric oxide production in children with malarial anemia: hemozoin-induced nitric oxide synthase type 2 transcripts and nitric oxide in blood mononuclear cells.. Infection and immunity. 72:4868-4873. 2004
- Naturally acquired hemozoin by monocytes promotes suppression of RANTES in children with malarial anemia through an IL-10-dependent mechanism.. Microbes and infection / Institut Pasteur. 11:811-819.
- Reduced peripheral PGE2 biosynthesis in Plasmodium falciparum malaria occurs through hemozoin-induced suppression of blood mononuclear cell cyclooxygenase-2 gene expression via an interleukin-10-independent mechanism.. Molecular medicine (Cambridge, Mass.). 10:45-54.
- Suppression of a novel hematopoietic mediator in children with severe malarial anemia.. Infection and immunity. 77:3864-3871.