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Publications in VIVO

McGuire, Paul G

Associate Dean Undergraduate Medical Education

Professor Cell Biology and Physiology


selected publications

research overview

  • Work in our laboratory focuses on the area of vascular cell biology and concentrates primarily on the molecular regulation of vascular permeability seen in diabetic retinopathy.  These studies make use of histological, biochemical and genetic techniques in both animal models of diabetes as well as in isolated vascular endothelial cells and pericytes.   Current studies examine the role of inflammatory mediators such as CCL2 in the regulation of monocyte recruitment and infiltration into the retina of diabetic animals and the role of pericyte-derrived Sphingosine 1-phosphate in the regulation of endothelial cell barrier function.

teaching overview

  • Gross anatomy, histology and embryology in the first year medical student curriculum