selected publications
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academic article
- Genetic landscape of chronic obstructive pulmonary disease identifies heterogeneous cell-type and phenotype associations. 2019
- Differences in microRNA expression in breast cancer between women of African and European ancestry.. Carcinogenesis. 40:61-69. 2019
- Early Detection of Lung Cancer Using DNA Promoter Hypermethylation in Plasma and Sputum.. Clinical cancer research : an official journal of the American Association for Cancer Research. 23:1998-2005. 2017
- Gene Methylation Biomarkers in Sputum and Plasma as Predictors for Lung Cancer Recurrence.. Cancer prevention research (Philadelphia, Pa.). 10:635-640. 2017
- Genetic loci associated with chronic obstructive pulmonary disease overlap with loci for lung function and pulmonary fibrosis. 2017
- miR-196b Is Epigenetically Silenced during the Premalignant Stage of Lung Carcinogenesis.. Cancer research. 76:4741-4751. 2016
- Methylation in Benign Prostate and Risk of Disease Progression in Men Subsequently Diagnosed with Prostate Cancer.. International journal of cancer. Journal international du cancer. :-. 2016
- Whole exome sequencing identifies novel candidate genes that modify chronic obstructive pulmonary disease susceptibility.. Human genomics. 10:-. 2016
- Radon Exposure, IL-6 Promoter Variants, and Lung Squamous Cell Carcinoma in Former Uranium Miners.. Environmental health perspectives. :-. 2015
- Epigenetic Repression of CCDC37 and MAP1B Links Chronic Obstructive Pulmonary Disease to Lung Cancer.. Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer. 10:1181-1188. 2015
- Implication of a Chromosome 15q15.2 Locus in Regulating UBR1 and Predisposing Smokers to MGMT Methylation in Lung.. Cancer research. :-. 2015
- Epigenetic change (GATA-4 gene methylation) is associated with health status in chronic obstructive pulmonary disease. 2015
- 15q12 Variants, Sputum Gene Promoter Hypermethylation, and Lung Cancer Risk: A GWAS in Smokers.. Journal of the National Cancer Institute. 107:-. 2015
- Global identification of genes targeted by DNMT3b for epigenetic silencing in lung cancer.. Oncogene. 34:621-630. 2015
- Unmasking the lung cancer epigenome.. Annual review of physiology. 77:453-474. 2015
- SGI-110 and entinostat therapy reduces lung tumor burden and reprograms the epigenome.. International journal of cancer. Journal international du cancer. 135:2223-2231. 2014
- Staff Perspectives on Juvenile Drug Court Operations: A Multi-Site Qualitative Study.. Criminal justice policy review. 25:614-636. 2014
- RIP1 maintains DNA integrity and cell proliferation by regulating PGC-1α-mediated mitochondrial oxidative phosphorylation and glycolysis.. Cell death and differentiation. 21:1061-1070. 2014
- GATA2 is epigenetically repressed in human and mouse lung tumors and is not requisite for survival of KRAS mutant lung cancer.. Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer. 9:784-793. 2014
- Genome-wide unmasking of epigenetically silenced genes in lung adenocarcinoma from smokers and never smokers.. Carcinogenesis. 35:1248-1257. 2014
- A Phase I Protocol of Hydralazine and Valproic Acid in Advanced, Previously Treated Solid Cancers.. Translational oncology. :-. 2014
- Functional identification of cancer-specific methylation of CDO1, HOXA9, and TAC1 for the diagnosis of lung cancer.. Clinical cancer research : an official journal of the American Association for Cancer Research. 20:1856-1864. 2014
- Rapid lung function decline in smokers is a risk factor for COPD and is attenuated by angiotensin-converting enzyme inhibitor use.. Chest. 145:695-703. 2014
- Increased methylation of lung cancer-associated genes in sputum DNA of former smokers with chronic mucous hypersecretion.. Respiratory research. 15:-. 2014
- MUC1 in macrophage: contributions to cigarette smoke-induced lung cancer.. Cancer research. 74:460-470. 2014
- Randomized, double-blind, placebo-controlled, phase III chemoprevention trial of selenium supplementation in patients with resected stage I non-small-cell lung cancer: ECOG 5597. 2013
- Aerosolised 5-azacytidine suppresses tumour growth and reprogrammes the epigenome in an orthotopic lung cancer model.. British journal of cancer. 109:1775-1781. 2013
- Genetic variation in SIRT1 affects susceptibility of lung squamous cell carcinomas in former uranium miners from the Colorado plateau.. Carcinogenesis. 34:1044-1050. 2013
- Softwares and methods for estimating genetic ancestry in human populations.. Human genomics. 7:-. 2013
- Native American ancestry affects the risk for gene methylation in the lungs of Hispanic smokers from New Mexico.. American journal of respiratory and critical care medicine. 188:1110-1116. 2013
- Sex-specific association of sequence variants in CBS and MTRR with risk for promoter hypermethylation in the lung epithelium of smokers.. Carcinogenesis. 33:1542-1547. 2012
- A phase I study of 5-azacytidine and erlotinib in advanced solid tumor malignancies.. Cancer chemotherapy and pharmacology. 69:547-554. 2012
- Genetic determinants for promoter hypermethylation in the lungs of smokers: a candidate gene-based study.. Cancer research. 72:707-715. 2012
- Methylated Genes in Sputum Among Older Smokers With Asthma.. Chest. 142:425-431. 2012
- The A/G allele of rs16906252 predicts for MGMT methylation and is selectively silenced in premalignant lesions from smokers and in lung adenocarcinomas.. Clinical cancer research : an official journal of the American Association for Cancer Research. 17:2014-2023. 2011
- The A/G allele of rs16906252 predicts for MGMT methylation and is selectively silenced in premalignant lesions from smokers and in lung adenocarcinomas.. Clinical cancer research : an official journal of the American Association for Cancer Research. 17:2014-2023. 2011
- Wood smoke exposure and gene promoter methylation are associated with increased risk for COPD in smokers.. American journal of respiratory and critical care medicine. 182:1098-1104. 2010
- Multivitamins, folate, and green vegetables protect against gene promoter methylation in the aerodigestive tract of smokers.. Cancer research. 70:568-574. 2010
- Difference in airflow obstruction between Hispanic and non-Hispanic White female smokers.. COPD. 5:274-281. 2008
- DNA methylation biomarkers to assess therapy and chemoprevention for non-small cell lung cancer.. Nutrition reviews. 66 Suppl 1:S24-S26. 2008
- Promoter hypermethylation of multiple genes in sputum precedes lung cancer incidence in a high-risk cohort. 2006
- Genotypes in matrix metalloproteinase 9 are a risk factor for COPD.. International journal of chronic obstructive pulmonary disease. 1:267-278. 2006
- Genotypes in matrix metalloproteinase 9 are a risk factor for COPD.. International journal of chronic obstructive pulmonary disease. 1:267-278. 2006
- Gene promoter methylation in plasma and sputum increases with lung cancer risk.. Clinical cancer research : an official journal of the American Association for Cancer Research. 11:6505-6511. 2005
- Silencing of genes by promoter hypermethylation: key event in rodent and human lung cancer.. Carcinogenesis. 26:1481-1487. 2005
- Multiplicity of abnormal promoter methylation in lung adenocarcinomas from smokers and never smokers.. International journal of cancer. 114:400-405. 2005
- Gene-promoter hypermethylation as a biomarker in lung cancer.. Nature reviews. Cancer. 4:707-717. 2004
- Plutonium targets the p16 gene for inactivation by promoter hypermethylation in human lung adenocarcinoma.. Carcinogenesis. 25:1063-1067. 2004
- Inhibition of DNA methylation and histone deacetylation prevents murine lung cancer. 2003
- Promoter hypermethylation of the O6-methylguanine-DNA methyltransferase gene: more common in lung adenocarcinomas from never-smokers than smokers and associated with tumor progression.. Cancer research. 63:4842-4848. 2003
- Aberrant promoter methylation in bronchial epithelium and sputum from current and former smokers. 2002
- Aberrant CpG island methylation of the p16(INK4a) and estrogen receptor genes in rat lung tumors induced by particulate carcinogens.. Carcinogenesis. 23:335-339. 2002
- Combination therapy with vidaza and entinostat suppresses tumor growth and reprograms the epigenome in an orthotopic lung cancer model.. Cancer research. 71:454-462.
- Discovery of common SNPs in the miR-205/200 family-regulated epithelial to mesenchymal transition pathway and their association with risk for non-small cell lung cancer.. International journal of molecular epidemiology and genetics. 2:145-155.
- New Mexican Hispanic smokers have lower odds of chronic obstructive pulmonary disease and less decline in lung function than non-Hispanic whites.. American journal of respiratory and critical care medicine. 184:1254-1260.
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document
- Epigenetics is alive and growing.. Trends in molecular medicine. 53-54. 2002
- Low plasma CC16 levels in smokers are associated with a higher risk for chronic bronchitis.. The European respiratory journal. -. 2015