selected publications
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academic article
- Repair of DNA double-strand breaks by mammalian alternative end-joining pathways.. The Journal of biological chemistry. 293:10536-10546. 2018
- Structure-activity relationships among DNA ligase inhibitors: Characterization of a selective uncompetitive DNA ligase I inhibitor.. DNA repair. 60:29-39. 2017
- Inhibiting Mitochondrial DNA Ligase IIIα Activates Caspase 1-Dependent Apoptosis in Cancer Cells.. Cancer research. 76:5431-5441. 2016
- Chromosomal translocations in human cells are generated by canonical nonhomologous end-joining.. Molecular cell. 55:829-842. 2014
- Structure and function of the DNA ligases encoded by the mammalian LIG3 gene.. Gene. 531:150-157. 2013
- Genomic instability in myeloid malignancies: increased reactive oxygen species (ROS), DNA double strand breaks (DSBs) and error-prone repair.. Cancer letter. 270:1-9. 2008
- Internal tandem duplication of FLT3 (FLT3/ITD) induces increased ROS production, DNA damage, and misrepair: implications for poor prognosis in AML.. Blood. 111:3173-3182. 2008
- Up-regulation of WRN and DNA ligase IIIalpha in chronic myeloid leukemia: consequences for the repair of DNA double-strand breaks.. Blood. 112:1413-1423. 2008