Publications in VIVO

Co-author Network

Hu, Chien-an "Andy" Associate Professor

Positions

Member, Women's Cancers Research Program, UNM Comprehensive Cancer Center , Department of Internal Medicine
Associate Professor, Department of Biochemistry & Molecular Biology , School of Medicine

Hu received an MS (1991) and PhD (1993) in molecular genetics from The Ohio State University. He completed a postdoctoral fellowship in human molecular genetics in 1997 at Howard Hughes Medical Institute, McKusick-Nathans Institute of Genetic Medicine, Department of Pediatrics and Department of Molecular Biology and Genetics, Johns Hopkins University School of Medicine. He served on the research faculty at McKusick-Nathans Institute of Genetic Medicine until he joined UNM in 2001.

Publications
Research
Background
Contact
View All

selected publications

academic article
- Hospitalization Trajectories and Risks of ESKD and Death in Individuals With CKD.. Kidney international reports. 6:1592-1602. 2021
- Statin use and the risk of renal cell carcinoma: national cohort study.. Journal of investigative medicine : the official publication of the American Federation for Clinical Research. 68:776-781. 2020
- The association between plasma selenium and chronic kidney disease related to lead, cadmium and arsenic exposure in a Taiwanese population.. Journal of hazardous materials. 375:224-232. 2019
- Baicalin modulates apoptosis via RAGE, MAPK, and AP-1 in vascular endothelial cells during Haemophilus parasuis invasion.. Innate immunity. :-. 2019
- Effect of Baicalin-Aluminum Complexes on Fecal Microbiome in Piglets.. International journal of molecular sciences. 20:-. 2019
- Effects of Baicalin on piglet monocytes involving PKC-MAPK signaling pathways induced by Haemophilus parasuis.. BMC veterinary research. 15:-. 2019
- Metabolism, Nutrition, and Redox Signaling of Hydroxyproline.. Antioxidants & redox signaling. 30:674-682. 2019
- Baicalin modulates NF-κB and NLRP3 inflammasome signaling in porcine aortic vascular endothelial cells Infected by Haemophilus parasuis Causing Glässer's disease.. Scientific reports. 8:-. 2018
- A Small Molecule BH3-mimetic Suppresses Cigarette Smoke-Induced Mucous Expression in Airway Epithelial Cells.. Scientific reports. 8:-. 2018
- Baicalin Inhibits Haemophilus Parasuis-Induced High-Mobility Group Box 1 Release during Inflammation.. International journal of molecular sciences. 19:-. 2018
- Transcriptional Profiling of Host Cell Responses to Virulent Haemophilus parasuis: New Insights into Pathogenesis.. International journal of molecular sciences. 19:-. 2018
- Asparagine preserves intestinal barrier function from LPS-induced injury and regulates CRF/CRFR signaling pathway.. Innate immunity. 23:546-556. 2017
- Functions of pregnane X receptor in self-detoxification.. Amino acids. 49:1999-2007. 2017
- Human interstitial cellular model in therapeutics of heart valve calcification.. Amino acids. 49:1981-1997. 2017
- L-Glutamine and L-arginine protect against enterotoxigenic Escherichia coli infection via intestinal innate immunity in mice.. Amino acids. 49:1945-1954. 2017
- N-Acetylcysteine improves intestinal function in lipopolysaccharides-challenged piglets through multiple signaling pathways.. Amino acids. 49:1915-1929. 2017
- N-Acetylcysteine supplementation alleviates intestinal injury in piglets infected by porcine epidemic diarrhea virus.. Amino acids. 49:1931-1943. 2017
- Roles of amino acids in preventing and treating intestinal diseases: recent studies with pig models.. Amino acids. 49:1277-1291. 2017
- The role of methionine on metabolism, oxidative stress, and diseases.. Amino acids. 49:2091-2098. 2017
- Zebrafish as a model to evaluate peptide-related cancer therapies.. Amino acids. 49:1907-1913. 2017
- Therapeutic Potential of Amino Acids in Inflammatory Bowel Disease.. Nutrients. 9:-. 2017
- Methionine restriction on oxidative stress and immune response in dss-induced colitis mice.. Oncotarget. 8:44511-44520. 2017
- Myokines and adipokines: Involvement in the crosstalk between skeletal muscle and adipose tissue.. Cytokine & growth factor reviews. 33:73-82. 2017
- Transgenic expression of human APOL1 risk variants in podocytes induces kidney disease in mice.. Nature medicine. :-. 2017
- Aspartate inhibits LPS-induced MAFbx and MuRF1 expression in skeletal muscle in weaned pigs by regulating Akt, AMPKα and FOXO1.. Innate immunity. 23:34-43. 2017
- DNA Methylation and the Potential Role of Methyl-Containing Nutrients in Cardiovascular Diseases.. Oxidative medicine and cellular longevity. 2017:-. 2017
- FGF19/FGFR4 signaling contributes to the resistance of hepatocellular carcinoma to sorafenib.. Journal of experimental & clinical cancer research : CR. 36:-. 2017
- β-Conglycinin enhances autophagy in porcine enterocytes.. Amino acids. 49:203-207. 2017
- Baicalin suppresses NLRP3 inflammasome and nuclear factor-kappa B (NF-κB) signaling during Haemophilus parasuis infection.. Veterinary research. 47:-. 2016
- Evaluation of recombinant protein superoxide dismutase of Haemophilus parasuis strain SH0165 as vaccine candidate in a mouse model.. Canadian journal of microbiology. :1-9. 2016
- Asparagine improves intestinal integrity, inhibits TLR4 and NOD signaling, and differently regulates p38 and ERK1/2 signaling in weanling piglets after LPS challenge.. Innate immunity. 22:577-587. 2016
- Variants in autophagy-related genes and clinical characteristics in melanoma: a population-based study.. Cancer medicine. 5:3336-3345. 2016
- Glycine Enhances Muscle Protein Mass Associated with Maintaining Akt-mTOR-FOXO1 Signaling and Suppressing TLR4 and NOD2 Signaling in Piglets Challenged with LPS.. American journal of physiology. Regulatory, integrative and comparative physiology. :-. 2016
- Amino acid deprivation disrupts barrier function and induces protective autophagy in intestinal porcine epithelial cells.. Amino acids. 47:2177-2184. 2015
- Amino acids and autophagy: their crosstalk, interplay and interlock.. Amino acids. 47:2035-2036. 2015
- Autophagy protects intestinal epithelial Cells against Deoxynivalenol toxicity by alleviating oxidative stress via IKK signaling pathway.. Free radical biology & medicine. :-. 2015
- Bioactive dietary peptides and amino acids in inflammatory bowel disease.. Amino acids. 47:2127-2141. 2015
- Erratum to: Amino acids and autophagy: their crosstalk, interplay and interlock.. Amino acids. :-. 2015
- How complicated can it be? The link between APOL1 risk variants and lipoprotein heterogeneity in kidney and cardiovascular diseases.. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association. :-. 2015
- Intimacy and a deadly feud: the interplay of autophagy and apoptosis mediated by amino acids.. Amino acids. 47:2089-2099. 2015
- N-acetylcysteine stimulates protein synthesis in enterocytes independently of glutathione synthesis.. Amino acids. :-. 2015
- Autophagy and tight junction proteins in the intestine and intestinal diseases.. Animal nutrition (Zhongguo xu mu shou yi xue hui). 1:123-127. 2015
- Iron-based superparamagnetic nanoparticle contrast agents for MRI of infection and inflammation. 2015
- Autophagy enhancement of intestinal epithelial tight junction barrier function by targeting claudin-2 degradation. 2015
- Signaling Pathways Related to Protein Synthesis and Amino Acid Concentration in Pig Skeletal Muscles Depend on the Dietary Protein Level, Genotype and Developmental Stages. 2015
- Tc-99m-labeled RGD-conjugated alpha-melanocyte stimulating hormone hybrid peptides with reduced renal uptake.. Amino acids. :-. 2015
- Amentoflavone inhibits angiogenesis of endothelial cells and stimulates apoptosis in hypertrophic scar fibroblasts.. Burns : journal of the International Society for Burn Injuries. 40:922-929. 2014
- Deacetylation of p53 induces autophagy by suppressing Bmf expression.. The Journal of cell biology. 201:427-437. 2013
- Autophagy regulates lipolysis and cell survival through lipid droplet degradation in androgen-sensitive prostate cancer cells.. The Prostate. 72:1412-1422. 2012
- Synergistic killing effect of chloroquine and androgen deprivation in LNCaP cells.. Biochemical and biophysical research communications. 425:150-156. 2012
- Human apolipoprotein L1 (ApoL1) in cancer and chronic kidney disease.. FEBS letters. 586:947-955. 2012
- Apolipoprotein L6, induced in atherosclerotic lesions, promotes apoptosis and blocks Beclin 1-dependent autophagy in atherosclerotic cells. 2011
- ApoL1, a BH3-only lipid-binding protein, induces autophagic cell death.. Autophagy. 4:1079-1082. 2008
- Functional genomics and SNP analysis of human genes encoding proline metabolic enzymes.. Amino acids. 35:655-664. 2008
- Human Delta1-pyrroline-5-carboxylate synthase: function and regulation.. Amino acids. 35:665-672. 2008
- Apolipoprotein L1, a novel Bcl-2 homology domain 3-only lipid-binding protein, induces autophagic cell death.. The Journal of biological chemistry. 283:21540-21549. 2008
- A novel loss-of-function mutation in TP53 in an endometrial cancer cell line and uterine papillary serous carcinoma model.. Molecular and cellular biochemistry. 297:179-187. 2007
- Overexpression of proline oxidase induces proline-dependent and mitochondria-mediated apoptosis.. Molecular and cellular biochemistry. 295:85-92. 2007
- PUMA overexpression induces reactive oxygen species generation and proteasome-mediated stathmin degradation in colorectal cancer cells. 2005
- Apolipoprotein l6, a novel proapoptotic Bcl-2 homology 3-only protein, induces mitochondria-mediated apoptosis in cancer cells.. Molecular cancer research : MCR. 3:21-31. 2005
- Large-scale quantitative proteomic study of PUMA-induced apoptosis using two-dimensional liquid chromatography-mass spectrometry coupled with amino acid-coded mass tagging.. Journal of proteome research. 3:1191-1200. 2004
- Global investigation of p53-induced apoptosis through quantitative proteomic profiling using comparative amino acid-coded tagging.. Molecular & cellular proteomics : MCP. 3:998-1008. 2004

editor of

academic article
- Amino Acids