Molecular biology of the cell
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Activated N-formyl peptide receptor and high-affinity IgE receptor occupy common domains for signaling and internalization.
Alternative splicing of SNAP-25 regulates secretion through nonconservative substitutions in the SNARE domain.
Markers for detergent-resistant lipid rafts occupy distinct and dynamic domains in native membranes.
Wortmannin-sensitive phosphorylation, translocation, and activation of PLCgamma1, but not PLCgamma2, in antigen-stimulated RBL-2H3 mast cells.
Wortmannin blocks lipid and protein kinase activities associated with PI 3-kinase and inhibits a subset of responses induced by Fc epsilon R1 cross-linking.