Bovine Pericardium for Dural Grafts: Clinical Results in 35 Patients Academic Article uri icon



    The United States Food and Drug Administration has recently approved the marketing of bovinepericardium as a dural graft material, but literature reports of this use are limited. Bovinepericardium has been widely used for grafts in cardiac surgery and seems to have suitable properties for use as a dural graft. We report the use of glutaraldehyde-processed bovinepericardium for duralgrafts in 35patients undergoing cranial and craniospinal operations with the objective of providing a clinical assessment of this material and technique.


    This report is a retrospective analysis of 35patients. All available records were reviewed and information regarding the indication for grafting, graft size, complications, and outcome were collected and analyzed for all patients.


    Indications for grafting included meningioma resection, posterior fossa craniotomy, Chiari decompression, dural-based metastases, and trauma. Outcomes were good or excellent in 32 patients; the three fair or poor outcomes were not related to surgical closure. In no patient was the dural graft a significant factor in outcome. Bovinepericardium was found to be easily sutured to be watertight using standard suture material. The material is relatively inexpensive and requires no additional incision. It has low antigenicity and toxicity, good strength, and minimal elasticity.


    In this clinical assessment, bovinepericardium was found to be an excellent dural graft material.

    Comment in PMID: 8880771 [PubMed - indexed for MEDLINE]

publication date

  • January 1, 1996