Nitrous oxide for pain management of first trimester surgical abortion - a randomized controlled pilot study. Academic Article uri icon


  • The objective was to determine feasibility of a study comparing mean pain scores between women randomized to nitrous oxide/oxygen (NO) versus oxygen+oral analgesics for trimester surgical abortion.Pilot randomized controlled trial comparing NO (n=10) versus oxygen+oral analgesics (n=10). Feasibility of subject recruitment, and pain and satisfaction scores on a visual analog scale were evaluated.Fifty-seven percent of eligible women participated. Mean pain scores were similar between groups, and mean satisfaction scores were higher for the NO group (77.5 vs. 46.7, P=.048).The majority of eligible women agreed to participate in this study evaluating an uncommon pain control intervention.Copyright © 2015 Elsevier Inc. All rights reserved.

publication date

  • February 2015